Purinergic signaling and blood vessels in health and disease
G Burnstock, V Ralevic - Pharmacological reviews, 2014 - ASPET
Purinergic signaling plays important roles in control of vascular tone and remodeling. There
is dual control of vascular tone by ATP released as a cotransmitter with noradrenaline from …
is dual control of vascular tone by ATP released as a cotransmitter with noradrenaline from …
Purinergic signalling in the gastrointestinal tract and related organs in health and disease
G Burnstock - Purinergic signalling, 2014 - Springer
Purinergic signalling plays major roles in the physiology and pathophysiology of digestive
organs. Adenosine 5′-triphosphate (ATP), together with nitric oxide and vasoactive …
organs. Adenosine 5′-triphosphate (ATP), together with nitric oxide and vasoactive …
[HTML][HTML] Enteric nervous system and inflammatory bowel diseases: Correlated impacts and therapeutic approaches through the P2X7 receptor
HIR Magalhães, P Castelucci - World Journal of Gastroenterology, 2021 - ncbi.nlm.nih.gov
The enteric nervous system (ENS) consists of thousands of small ganglia arranged in the
submucosal and myenteric plexuses, which can be negatively affected by Crohn's disease …
submucosal and myenteric plexuses, which can be negatively affected by Crohn's disease …
The role of purinergic pathways in the pathophysiology of gut diseases: pharmacological modulation and potential therapeutic applications
Gut homeostasis results from complex neuro-immune interactions aimed at triggering
stereotypical and specific programs of coordinated mucosal secretion and powerful motor …
stereotypical and specific programs of coordinated mucosal secretion and powerful motor …
The role of extracellular adenosine triphosphate in ischemic organ injury
Objectives: Ischemic tissue injury contributes to significant morbidity and mortality and is
implicated in a range of pathologic conditions, including but not limited to myocardial …
implicated in a range of pathologic conditions, including but not limited to myocardial …
Differential effects of experimental ulcerative colitis on P2X7 receptor expression in enteric neurons
MV Da Silva, AR Marosti, CE Mendes… - Histochemistry and cell …, 2015 - Springer
The digestive tracts of ulcerative colitis and Crohn's disease patients present with
pathophysiological processes and intestinal necrosis. This study examined the P2X7 …
pathophysiological processes and intestinal necrosis. This study examined the P2X7 …
Submucosal neurons and enteric glial cells expressing the P2X7 receptor in rat experimental colitis
MV da Silva, AR Marosti, CE Mendes, K Palombit… - Acta …, 2017 - Elsevier
The aim of this study was to evaluate the effect of ulcerative colitis on the submucosal
neurons and glial cells of the submucosal ganglia of rats. 2, 4, 6-Trinitrobenzene sulfonic …
neurons and glial cells of the submucosal ganglia of rats. 2, 4, 6-Trinitrobenzene sulfonic …
Experimental cancer cachexia changes neuron numbers and peptide levels in the intestine: partial protective effects after dietary supplementation with L-glutamine
GE Vicentini, L Fracaro, SRG de Souza, HA Martins… - Plos one, 2016 - journals.plos.org
Gastrointestinal dysmotility frequently occurs in cancer cachexia and may result from
damage to enteric innervation caused by oxidative stress, especially due to glutathione …
damage to enteric innervation caused by oxidative stress, especially due to glutathione …
Effects of probenecid and brilliant blue G on rat enteric glial cells following intestinal ischemia and reperfusion
CE Mendes, K Palombit, TTA Pereira, HIR Magalhães… - Acta …, 2023 - Elsevier
The P2X7 receptor participates in several intracellular events and acts with the pannexin-1
channel. This study examined the effects of probenecid (PB) and brilliant blue G (BBG) …
channel. This study examined the effects of probenecid (PB) and brilliant blue G (BBG) …
Effects of ischemia and reperfusion on subpopulations of rat enteric neurons expressing the P2X7 receptor
K Palombit, CE Mendes, W Tavares-de-Lima… - Digestive diseases and …, 2013 - Springer
Background Intestinal ischemia followed by reperfusion (I/R) may occur following intestinal
obstruction. In rats, I/R in the small intestine leads to structural changes accompanied by …
obstruction. In rats, I/R in the small intestine leads to structural changes accompanied by …