Cryptococcal meningitis

L Tugume, K Ssebambulidde, J Kasibante… - Nature Reviews …, 2023 - nature.com
Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Cryptococcosis

AC Gushiken, KK Saharia, JW Baddley - Infectious Disease Clinics, 2021 - id.theclinics.com
Cryptococcosis is an infection of global significance, affecting both immunocompromised
and immunocompetent hosts. Traditionally, 2 main species of yeasts caused cryptococcosis …

Diagnosis and management of cryptococcal meningitis in HIV-infected adults

TC McHale, DR Boulware, J Kasibante… - Clinical microbiology …, 2023 - Am Soc Microbiol
Cryptococcal meningitis is a leading cause of morbidity and mortality globally, especially in
people with advanced HIV disease. Cryptococcal meningitis is responsible for nearly 20% of …

Cryptococcal antigen in serum and cerebrospinal fluid for detecting cryptococcal meningitis in adults living with human immunodeficiency virus: systematic review and …

E Temfack, JJB Rim, R Spijker, A Loyse… - Clinical Infectious …, 2021 - academic.oup.com
Cryptococcal antigen (CrAg) detection could direct the timely initiation of antifungal therapy.
We searched MEDLINE and Embase for studies where CrAg detection in …

Methods for rapid diagnosis of meningitis etiology in adults

V Poplin, DR Boulware, NC Bahr - Biomarkers in medicine, 2020 - Taylor & Francis
Infectious meningitis can be caused by viral, bacterial or fungal pathogens. Despite widely
available treatments, many types of infectious meningitis are still associated with significant …

The changing epidemiology of HIV-associated adult meningitis, Uganda 2015–2017

J Ellis, AS Bangdiwala, FV Cresswell… - Open forum …, 2019 - academic.oup.com
Background Central nervous system (CNS) infections remain a major public health problem
in Sub-Saharan Africa, causing 15%–25% of AIDS-related deaths. With widespread …

Cryptococcal antigenemia in advanced human immunodeficiency virus disease: pathophysiology, epidemiology, and clinical implications

RM Wake, SF Molloy, JN Jarvis… - Clinical Infectious …, 2023 - academic.oup.com
Cryptococcal antigen (CrAg) is detectable in blood prior to the onset of symptomatic
cryptococcal meningitis (CM), a leading cause of death among people with advanced …

Evaluation of the BioFire® FilmArray® Meningitis/Encephalitis panel in an adult and pediatric Ugandan population

S Bridge, KH Hullsiek, C Nerima, EE Evans… - Journal of Medical …, 2021 - Elsevier
Background Meningitis causes significant mortality in sub-Saharan Africa and limited
diagnostics exist. We evaluated the utility of the BioFire® FilmArray® Meningitis/Encephalitis …

[HTML][HTML] Evaluation of the Biofire FilmArray meningitis/encephalitis assay for the detection of Cryptococcus neoformans/gattii

TT Van, TH Kim, SM Butler-Wu - Clinical Microbiology and Infection, 2020 - Elsevier
Objectives Cryptococcal meningitis (CM) remains an important cause of morbidity and
mortality among immunocompromised patients. Laboratory diagnostics for CM includes …

Adjunctive Single-Dose Liposomal Amphotericin to Prevent Cryptococcal Meningitis in People With Human Immunodeficiency Virus (HIV)–Associated Cryptococcal …

DB Meya, E Nalintya, CP Skipper… - Clinical Infectious …, 2024 - academic.oup.com
Background Cryptococcal meningitis is a leading cause of AIDS-related mortality.
Cryptococcal antigen (CrAg) predicts the development of meningitis. Historically, despite …