Photophysical processes in single molecule organic fluorescent probes
EMS Stennett, MA Ciuba, M Levitus - Chemical Society Reviews, 2014 - pubs.rsc.org
The use of organic fluorescent probes in biochemical and biophysical applications of single
molecule spectroscopy and fluorescence microscopy techniques continues to increase. As …
molecule spectroscopy and fluorescence microscopy techniques continues to increase. As …
Methods for physical characterization of phase-separated bodies and membrane-less organelles
Membrane-less organelles are cellular structures which arise through the phenomenon of
phase separation. This process enables compartmentalization of specific sets of …
phase separation. This process enables compartmentalization of specific sets of …
[HTML][HTML] Transbilayer lipid interactions mediate nanoclustering of lipid-anchored proteins
Understanding how functional lipid domains in live cell membranes are generated has
posed a challenge. Here, we show that transbilayer interactions are necessary for the …
posed a challenge. Here, we show that transbilayer interactions are necessary for the …
Practical guidelines for dual-color fluorescence cross-correlation spectroscopy
K Bacia, P Schwille - Nature protocols, 2007 - nature.com
Dual-color fluorescence cross-correlation spectroscopy (FCCS) allows for the determination
of molecular mobility and concentrations and for the quantitative analysis of molecular …
of molecular mobility and concentrations and for the quantitative analysis of molecular …
The nature of the amyloid-β monomer and the monomer-oligomer equilibrium
The monomer to oligomer transition initiates the aggregation and pathogenic transformation
of Alzheimer's Amyloid-β (Aβ) peptide. However, the monomeric state of this aggregation …
of Alzheimer's Amyloid-β (Aβ) peptide. However, the monomeric state of this aggregation …
Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes
D Rabuka, MB Forstner, JT Groves… - Journal of the American …, 2008 - ACS Publications
The controlled addition of structurally defined components to live cell membranes can
facilitate the molecular level analysis of cell surface phenomena. Here we demonstrate that …
facilitate the molecular level analysis of cell surface phenomena. Here we demonstrate that …
Development of a rhodamine–rhodanine-based fluorescent mercury sensor and its use to monitor real-time uptake and distribution of inorganic mercury in live …
We introduce a new rhodamine–rhodanine-based “turn-on” fluorescent sensor (RR1) and
describe its application for detection of mercury, including in solution, in live cells, and in a …
describe its application for detection of mercury, including in solution, in live cells, and in a …
Diffusivity of asphaltene molecules by fluorescence correlation spectroscopy
Using fluorescence correlation spectroscopy (FCS) we measure the translational diffusion
coefficient of asphaltene molecules in toluene at extremely low concentrations (0.03− 3.0 …
coefficient of asphaltene molecules in toluene at extremely low concentrations (0.03− 3.0 …
The Amyloid β Peptide (Aβ1-40) Is Thermodynamically Soluble at Physiological Concentrations
Precipitation of the 39− 43-residue amyloid β peptide (Aβ) is a crucial factor in Alzheimer's
disease (AD). In normal as well as in AD-afflicted brain, the Aβ concentration is estimated to …
disease (AD). In normal as well as in AD-afflicted brain, the Aβ concentration is estimated to …
Significant structural differences between transient amyloid‐β oligomers and less‐toxic fibrils in regions known to harbor familial alzheimer′ s mutations
Small oligomers of the amyloid β (Aβ) peptide, rather than the monomers or the fibrils, are
suspected to initiate Alzheimer′ s disease (AD). However, their low concentration and …
suspected to initiate Alzheimer′ s disease (AD). However, their low concentration and …