[HTML][HTML] Sarcopenia–Molecular mechanisms and open questions

P Wiedmer, T Jung, JP Castro, LCD Pomatto… - Ageing research …, 2021 - Elsevier
Sarcopenia represents a muscle-wasting syndrome characterized by progressive and
generalized degenerative loss of skeletal muscle mass, quality, and strength occurring …

[HTML][HTML] Myosteatosis in the context of skeletal muscle function deficit: an interdisciplinary workshop at the National Institute on Aging

R Correa-de-Araujo, O Addison, I Miljkovic… - Frontiers in …, 2020 - frontiersin.org
Skeletal muscle fat infiltration (known as myosteatosis) is an ectopic fat depot that increases
with aging and is recognized to negatively correlate with muscle mass, strength, and mobility …

[HTML][HTML] Resistance exercise training as a primary countermeasure to age-related chronic disease

JC Mcleod, T Stokes, SM Phillips - Frontiers in Physiology, 2019 - frontiersin.org
Age is a primary risk factor for a number of chronic diseases including mobility disability,
cardiovascular disease (CVD), type 2 diabetes (T2D), and cancer. Most physical activity …

[HTML][HTML] An elusive consensus definition of sarcopenia impedes research and clinical treatment: A narrative review

G Coletta, SM Phillips - Ageing Research Reviews, 2023 - Elsevier
The definition of sarcopenia, the age-related loss of muscle mass, has evolved since the
term's inception and yet there is no consensus. Many of the identified definitions of …

Sarcopenia and cardiovascular diseases

AA Damluji, M Alfaraidhy, N AlHajri, NN Rohant… - Circulation, 2023 - Am Heart Assoc
Sarcopenia is the loss of muscle strength, mass, and function, which is often exacerbated by
chronic comorbidities including cardiovascular diseases, chronic kidney disease, and …

The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates

SA Studenski, KW Peters, DE Alley… - … Series A: Biomedical …, 2014 - academic.oup.com
Background. Low muscle mass and weakness are common and potentially disabling in
older adults, but in order to become recognized as a clinical condition, criteria for diagnosis …

Intermuscular adipose tissue in metabolic disease

BH Goodpaster, BC Bergman, AM Brennan… - Nature Reviews …, 2023 - nature.com
Intermuscular adipose tissue (IMAT) is a distinct adipose depot described in early reports as
a 'fatty replacement'or 'muscle fat infiltration'that was linked to ageing and neuromuscular …

Frailty assessment in the cardiovascular care of older adults

J Afilalo, KP Alexander, MJ Mack, MS Maurer… - Journal of the American …, 2014 - jacc.org
Due to the aging and increasingly complex nature of our patients, frailty has become a high-
priority theme in cardiovascular medicine. Despite the recognition of frailty as a pivotal …

A review of sarcopenia: Enhancing awareness of an increasingly prevalent disease

E Marty, Y Liu, A Samuel, O Or, J Lane - Bone, 2017 - Elsevier
Sarcopenia is defined as an age associated decline in skeletal muscle mass. The
pathophysiology of sarcopenia is multifactorial, with decreased caloric intake, muscle fiber …

Gut microbiota contribute to age-related changes in skeletal muscle size, composition, and function: biological basis for a gut-muscle axis

GJ Grosicki, RA Fielding, MS Lustgarten - Calcified tissue international, 2018 - Springer
Skeletal muscle is a highly plastic tissue that plays a central role in human health and
disease. Aging is associated with a decrease in muscle mass and function (sarcopenia) that …