Within the cell, several mechanisms exist to maintain homeostasis of the endoplasmic
reticulum (ER). One of the primary mechanisms is the unfolded protein response (UPR). In …

Cadmium (Cd) is a non-essential transition metal which is introduced into the biosphere by
various anthropogenic activities. Environmental pollution with Cd poses a major health risk …

Cadmium (Cd) is present in food at low levels and accumulates in humans throughout life
because it is not effectively excreted. Cd from smoking or occupational exposure shows …

Cadmium (Cd) is a common heavy metal pollutant, and one of the important target organs of
its toxicity is the testis. Selenium (Se) has the ability to antagonize the toxicity of Cd …

Inducing early apoptosis in alveolar macrophages is one of the strategies influenza A virus
(IAV) evolved to subvert host immunity. Correspondingly, the host mitochondrial protein …

Cytisine, a quinolizidine alkaloid, is one of the major bioactive components found in the
small tree Sophora Alopecuraides L., and is a traditional Chinese medicine that is used for …

Chronic exposure to cadmium (Cd) is known to adversely affect renal function. Our previous
studies indicated that Cd induces p53-dependent apoptosis by inhibiting gene expression of …

HIV-associated neurocognitive impairment (HIV-NCI) is a debilitating comorbidity that
reduces quality of life in 15–40% of people with HIV (PWH) taking antiretroviral therapy …

Cadmium is a toxic metal contained in food, water and the atmosphere, and exposure to
cadmium can cause respiratory diseases in humans. Various health problems caused by …

Background/Aims: FBXO6 is the substrate recognition component of a Skp1-Cullin1-F-box
protein (SCF) ubiquitin E3 ligase complex, recognizing the chitobiose in unfolded N …