Immune checkpoint inhibitors (ICI) bind to programmed cell death-1 (PD-1)/PD-1 ligand-1
(PD-L1) and Cytotoxic T-lymphocyte antigen-4 (CTLA-4), which suppress T-cell function and …

Introduction Immune checkpoint inhibitors (ICIs) only benefit a subset of cancer patients,
underlining the need for predictive biomarkers for patient selection. Given the limitations of …

Simple Summary BCG immunotherapy plays an important role in bladder cancer treatment.
Unfortunately, we do not know how exactly the tumor microenvironment influences cancer …

Objective: The aim of this investigation was to explore the correlation between the levels of
tumor-infiltrating CD8+ and CD4+ T cells and the quantitative pharmacokinetic parameters …

Background Despite the recognized therapeutic potential of programmed cell death protein
1/programmed death‐ligand 1 (PD‐1/PD‐L1) inhibitors in advanced esophageal squamous …

Objective To explore the effectiveness of machine learning classifiers based on dynamic
contrast-enhanced magnetic resonance imaging (DCE-MRI) in predicting the expression …

Background and purpose Immune therapy with checkpoint inhibitors (CPIs) is a highly
successful therapy in many cancers including metastatic melanoma. Still, many patients do …

To investigate the expression, clinical significance, mechanism of action, and tumor
microenvironment (TME) of eight subunits of the chaperonin-containing TCP1 complex …

Introduction: A tumor microenvironment plays an important role in bladder cancer
development and in treatment response. Purpose: The aim of the study was to assess how …

Objective To explore the effectiveness of machine learning classifiers based on dynamic
contrast-enhanced magnetic resonance imaging (DCE-MRI) in predicting the expression …