Bone regeneration repairs bone tissue lost due to trauma, fractures, and tumors, or absent
due to congenital disorders. The extracellular matrix (ECM) is an intricate dynamic bio …

Mesenchymal stromal cells (MSCs) are a subset of heterogeneous non-hematopoietic
fibroblast-like cells that can differentiate into cells of multiple lineages, such as …

The multidisciplinary fields of tissue engineering and regenerative medicine have the
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …

Cell-derived extracellular matrices (CD-ECMs) captured increasing attention since the first
studies in the 1980s. The biological resemblance of CD-ECMs to their in vivo counterparts …

Tissue engineering and regenerative medicine have shown potential in the repair and
regeneration of tissues and organs via the use of engineered biomaterials and scaffolds …

Engineering biomaterials that mimic the extracellular matrix (ECM) of bone is of significant
importance since most of the outstanding properties of the bone are due to matrix …

Stem cell differentiation is of great interest in medical research; however, specifically and
effectively regulating stem cell differentiation is still a challenge. In addition to chemical …

Background Bone tissue engineering is a new concept bringing hope for the repair of large
bone defects, which remains a major clinical challenge. The formation of vascularized bone …

Mesenchymal stromal cells (MSC) have been proposed as an emerging cell-based
therapeutic option for regenerative medicine applications as these cells can promote tissue …

Cell source is the key to decellularized matrix (DM) strategy. This study compared 3 cell
types, osteocytes with/without dominant active Wnt/β-catenin signaling (daCO and WTO) …