Altered lipid metabolism is among the most prominent metabolic alterations in cancer.
Enhanced synthesis or uptake of lipids contributes to rapid cancer cell growth and tumor …

Lysophosphatidic acid (LPA) refers to a family of simple phospholipids that act as ligands for
G protein-coupled receptors. While LPA exerts effects throughout the body in normal …

INTRODUCTION Cells migrate over long distances during normal embryonic development
and in disease, and they navigate through complex, branched paths. Chemotaxis, cell …

The complexity and diversity of the biochemical processes that occur during tumorigenesis
and metastasis are frequently over-simplified in the traditional in vitro cell cultures. Two …

ABSTRACT E-cadherin is the main component of epithelial adherens junctions (AJs), which
play a crucial role in the maintenance of stable cell–cell adhesion and overall tissue …

Chemotaxis is a widespread mechanism that allows migrating cells to steer to where they
are needed. Attractant gradients may be imposed by external sources, or self-generated …

Self-organization is a key feature of many biological and developmental processes,
including cell migration. Although cell migration has traditionally been viewed as a …

Chemotaxis, where cell movement is steered by chemical gradients, is a widespread and
essential way of organising cell behaviour. But where do the instructions come from–who …

All free-living microorganisms homeostatically maintain the fluidity of their membranes by
adapting lipid composition to environmental temperatures. Here, we quantify enzymes and …

Liver cancer is one of the leading causes of death worldwide due to late diagnosis and
scarcity of treatment options. The major risk factor for liver cancer is cirrhosis with the …