In this review, selected recent advances in the preparation and reactivity of aziridines using
modern synthetic approaches are highlighted, while comparing these new strategies with …

Compounds featuring aziridine moieties are widely known and extensively reported in the
literature. Due to their great potential from both synthetic and pharmacological points of …

Boron-homologation reactions represent an efficient and programmable approach to
prepare alkylboronates, which are valuable and versatile synthetic intermediates. The …

We report the Sonogashira cross-coupling of aryl ammonium salts catalyzed by air-and
moisture-stable [Pd (NHC)(3-CF3-An) Cl2](An= aniline). This highly active Pd (II)–NHC …

Trifluoromethylated aziridines are the smallest fluorinated N-heterocycle and represent
important strategic building blocks with broad application in drug discovery for the synthesis …

The Matteson-type reactions have received increasing interest in constructing complex
organic molecules via iterative synthetic strategies; however, the current tactics are almost …

The homologation of Weinreb amides into difluoromethylketones with a formal nucleophilic
CHF2 transfer agent is reported. Activating TMSCHF2 with potassium tert-amylate enables a …

Due to the well known reactivity of C (O)–N functionalities towards canonical C1-
homologating agents (eg carbenoids, diazomethane, ylides), resulting in the extrusion of the …

The value of Matteson‐type reactions has been increasingly recognized for developing
automated organic synthesis. However, the typical Matteson reactions almost exclusively …

Abstract A formal CH2− CH2 homologation conducted with C1 carbenoids on a carbon
electrophile for the obtainment of a four‐membered cycle is reported. The logic proposes the …