[HTML][HTML] Artificial intelligence in sickle disease

AA Elsabagh, M Elhadary, B Elsayed, AM Elshoeibi… - Blood Reviews, 2023 - Elsevier
Artificial intelligence (AI) is rapidly becoming an established arm in medical sciences and
clinical practice in numerous medical fields. Its implications have been rising and are being …

Genotypic and phenotypic composition of sickle cell disease in the Arab population-a systematic review

F Ata, A Rahhal, L Malkawi, P Iqbal… - Pharmacogenomics …, 2023 - Taylor & Francis
Sickle cell disease (SCD) is a genetic disease influenced by ethnicity and regional
differences in its clinical course. Recent advances in the management of SCD with newer …

The liver in sickle cell disease

E Theocharidou, AR Suddle - Clinics in liver disease, 2019 - liver.theclinics.com
Sickle cell disease (SCD) or homozygous sickle cell anemia is the most common inherited
disorder of erythrocytes, characterized by the presence of pathologic hemoglobin S (HbS). A …

[HTML][HTML] Iron as a therapeutic target in chronic liver disease

E Kouroumalis, I Tsomidis… - World Journal of …, 2023 - ncbi.nlm.nih.gov
It was clearly realized more than 50 years ago that iron deposition in the liver may be a
critical factor in the development and progression of liver disease. The recent clarification of …

[HTML][HTML] Statural growth and prevalence of endocrinopathies in relation to liver iron content (LIC) in adult patients with beta thalassemia major (BTM) and sickle cell …

MA Yassin, AT Soliman, V De Sanctis… - Acta Bio Medica …, 2018 - ncbi.nlm.nih.gov
Despite regular blood transfusion and iron chelation therapy, growth impairment and
pubertal delay are commonly seen in children and adolescents with transfusion-dependent …

[HTML][HTML] Transfusion practice, post-transfusion complications and risk factors in Sickle Cell Disease in Senegal, West Africa

M Seck, AB Senghor, M Loum, SA Touré… - … of Hematology and …, 2022 - ncbi.nlm.nih.gov
Materials and Methods This case-control study included 253 SCD (153 SCD-transfused and
100 SCD non-transfused). We evaluated the transfusion practice (modalities, indications) …

Molecular mechanisms of hepatic dysfunction in sickle cell disease: Lessons from Townes mouse model

T Pradhan-Sundd, GJ Kato… - American Journal of …, 2022 - journals.physiology.org
Sickle cell disease (SCD) is an autosomal recessive genetic disorder that affects∼ 100,000
Americans and millions of people worldwide. Erythrocyte sickling, vaso-occlusion, sterile …

[HTML][HTML] Economic evaluation of chelation regimens for β-thalassemia major: a systematic review

J Li, Y Lin, X Li, J Zhang - Mediterranean Journal of Hematology …, 2019 - ncbi.nlm.nih.gov
Background Deferoxamine (DFO) or Deferiprone (DFP) or Deferasirox (DFX) monotherapy
and DFO and DFP combination therapy (DFO+ DFP) were four commonly implemented now …

Acute sickle cell hepatopathy: A case report and literature review

M Hassanzadeh, ZM Sanat, S Khayatian… - Journal of the National …, 2024 - Elsevier
Sickle cell disease (SCD) is an inherited hemoglobinopathy with protean clinical
manifestations. The liver could be affected by various SCD-associated complications of an …

The role of MRI-R2* in the detection of subclinical pancreatic iron loading among transfusion-dependent sickle cell disease patients and correlation with hepatic and …

BM Raief Mosaad, AS Ibrahim, MG Mansour… - Insights into …, 2022 - Springer
Objectives Pancreatic reserve could be preserved by early assessment of pancreatic iron
overload among transfusion-dependent sickle cell disease (SCD) patients. This study aimed …