Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery

AB Buya, A Beloqui, PB Memvanga, V Préat - Pharmaceutics, 2020 - mdpi.com
Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …

Controversies with self-emulsifying drug delivery system from pharmacokinetic point of view

B Chatterjee, S Hamed Almurisi… - Drug …, 2016 - Taylor & Francis
Self-emulsifying drug delivery system (SEDDS) is an isotropic mixture of lipid, surfactant and
co-surfactant, which forms a fine emulsion when comes in contact of an aqueous medium …

Novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for oral delivery of olmesartan medoxomil: design, formulation, pharmacokinetic and …

A Nasr, A Gardouh, M Ghorab - Pharmaceutics, 2016 - mdpi.com
The main purpose of this study was to develop a solid self-nanoemulsifying drug delivery
system (S-SNEDDS) of Olmesartan (OLM) for enhancement of its solubility and dissolution …

[HTML][HTML] In vitro and in vivo correlation for lipid-based formulations: Current status and future perspectives

Y Huang, Q Yu, Z Chen, W Wu, Q Zhu, Y Lu - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Lipid-based formulations (LBFs) have demonstrated a great potential in enhancing the oral
absorption of poorly water-soluble drugs. However, construction of in vitro and in vivo …

3D printing of dapagliflozin containing self-nanoemulsifying tablets: Formulation design and in vitro characterization

MS Algahtani, AA Mohammed, J Ahmad, MM Abdullah… - Pharmaceutics, 2021 - mdpi.com
The 3D printing techniques have been explored extensively in recent years for
pharmaceutical manufacturing and drug delivery applications. The current investigation …

Development and pharmacokinetic evaluation of Neusilin® US2-based S-SNEDDS tablets for bosentan: Fasted and fed states bioavailability, IVIS® real-time …

DY Usta, S Olgac, B Timur, ZS Teksin - International Journal of …, 2023 - Elsevier
The study reported here aimed to develop and optimize the S-SNEDDS tablet of bosentan
(BOS) and to investigate its pharmacokinetic and biodistribution properties. The BOS-loaded …

Exploring role of probiotics and Ganoderma lucidum extract powder as solid carriers to solidify liquid self-nanoemulsifying delivery systems loaded with curcumin

R Khursheed, SK Singh, S Wadhwa, M Gulati… - Carbohydrate …, 2020 - Elsevier
Solid self-nanoemulsifying drug delivery system (S-SENDDS) containing Curcumin (CRM)
were prepared using combination of Ganoderma lucidum extract powder (GLEP) and …

Development of guar gum-pectin-based colon targeted solid self-nanoemulsifying drug delivery system of xanthohumol

M Hanmantrao, S Chaterjee, R Kumar, S Vishwas… - Pharmaceutics, 2022 - mdpi.com
Present study deciphers development of oral polysaccharide-based colon targeted solid self-
nanoemulsifying drug delivery system (S-SNEDDS) of xanthohumol (XH). Several studies …

Solid self-nanoemulsifying drug delivery systems for oral delivery of polypeptide-k: formulation, optimization, in-vitro and in-vivo antidiabetic evaluation

V Garg, P Kaur, SK Singh, B Kumar, P Bawa… - European Journal of …, 2017 - Elsevier
Abstract Development of self-nanoemulsifying drug delivery systems (SNEDDS) of
polypeptide-k (PPK) is reported with the aim to achieve its oral delivery. Box-Behnken …

Development of mushroom polysaccharide and probiotics based solid self-nanoemulsifying drug delivery system loaded with curcumin and quercetin to improve their …

R Khursheed, SK Singh, S Wadhwa, M Gulati… - International Journal of …, 2021 - Elsevier
The role of mushroom polysaccharides and probiotics as pharmaceutical excipients for
development of nanocarriers has never been explored. In the present study an attempt has …