The model [NiFe]-hydrogenases of Escherichia coli

F Sargent - Advances in microbial physiology, 2016 - Elsevier
In Escherichia coli, hydrogen metabolism plays a prominent role in anaerobic physiology.
The genome contains the capability to produce and assemble up to four [NiFe] …

Protein fibrillation under crowded conditions

AH Gorensek-Benitez, B Kirk, JK Myers - Biomolecules, 2022 - mdpi.com
Protein amyloid fibrils have widespread implications for human health. Over the last twenty
years, fibrillation has been studied using a variety of crowding agents to mimic the packed …

Inhibition of insulin fibrillation by osmolytes: Mechanistic Insights

S Choudhary, N Kishore, RV Hosur - Scientific reports, 2015 - nature.com
We have studied here using a number of biophysical tools the effects of osmolytes, betaine,
citrulline, proline and sorbitol which differ significantly in terms of their physical …

Full-length TDP-43 and its C-terminal domain form filaments in vitro having non-amyloid properties

C Capitini, G Fani, M Vivoli Vega, A Penco, C Canale… - Amyloid, 2021 - Taylor & Francis
Accumulation of ubiquitin-positive, tau-and α-synuclein-negative intracellular inclusions of
TDP-43 in the central nervous system represents the major hallmark correlated to …

[PDF][PDF] Biological wonders of osmolytes: the need to know more

E Judy, N Kishore - Biochem. Anal. Biochem, 2016 - academia.edu
Nature has selected osmolytes to protect intracellular macromolecules against denaturing
stress conditions. These molecules are accumulated in the intracellular environment at …

Protein folding and stability in the presence of osmolytes

AV Fonin, VN Uversky, IM Kuznetsova, KK Turoverov - Biophysics, 2016 - Springer
Osmolytes are molecules whose function, among others, is to balance the hydrostatic
pressure between the intracellular and extracellular compartments. Accumulation of …

Фолдинг и стабильность белка в присутствии осмолитов

АВ Фонин, ВН Уверский, ИМ Кузнецова… - Биофизика, 2016 - elibrary.ru
Осмолиты-молекулы, одной из функций которых является выравнивание
гидростатического давления между внутри-и внеклеточным пространством. Осмолиты …