Advances in 2‐substituted benzothiazole scaffold‐based chemotherapeutic agents

K Haider, S Rehman, A Pathak, AK Najmi… - Archiv der …, 2021 - Wiley Online Library
Targeted therapy plays a pivotal role in cancer therapeutics by countering the drawbacks of
conventional treatment like adverse events and drug resistance. Over the last decade …

Advancement in pharmacological activities of benzothiazole and its derivatives: An up to date review

A Kumar, AK Mishra - Mini Reviews in Medicinal Chemistry, 2021 - ingentaconnect.com
Benzothiazole is a heterocyclic aromatic and bicyclic compound in which, benzene ring is
attached with thiazole ring. This nucleus is established in marine as well as terrestrial …

[HTML][HTML] Thiazolidin-4-ones as potential antimicrobial agents: Experimental and in silico evaluation

C Tratrat, A Petrou, A Geronikaki, M Ivanov, M Kostić… - Molecules, 2022 - mdpi.com
Herein, we report computational and experimental evaluations of the antimicrobial activity of
twenty one 2, 3-diaryl-thiazolidin-4-ones. All synthesized compounds exhibited an …

[HTML][HTML] Solid-Phase Synthesis of 2-Benzothiazolyl and 2-(Aminophenyl) benzothiazolyl Amino Acids and Peptides

S Mourtas, V Athanasopoulos, D Gatos, K Barlos - Molecules, 2023 - mdpi.com
2-benzothiazoles and 2-(aminophenyl) benzothiazoles represent biologically interesting
heterocycles with high pharmacological activity. The combination of these heterocycles with …

In-vitro Screening of Anti-microbial, Anti-fungal and Anti-oxidant activities of Ethanolic leaf extract of Anthocephalus cadamba

N Priyanka, M Srikanth, GR Babu… - Asian Journal of …, 2022 - indianjournals.com
Anthocephalus cadamba, Rubiaceae, is a medicinal herb of great importance for traditional
applications against several disease kinds. Because of the range of compounds, the genus …

[HTML][HTML] Benzothiazole and chromone derivatives as potential ATR kinase inhibitors and anticancer agents

M Frasinyuk, D Chhabria, V Kartsev, H Dilip… - Molecules, 2022 - mdpi.com
Despite extensive studies and the great variety of existing anticancer agents, cancer
treatment remains an aggravating and challenging problem. Therefore, the development of …

Design, Synthesis, Antimicrobial and Docking Studies of Benzothiazoles Bearing Pyrazole and Pyrimidine Moieties

E Tamam, AA Fadda, ER El‐Sawy… - …, 2023 - Wiley Online Library
The reaction of enaminonitrile 2 with hydrazine hydrate yielded 5‐amino pyrazole derivative
4. Compound 4 reacted with ethyl acetoacetate, enaminone 8, chalcone 12, enaminonitrile …

Synthesis, molecular docking, and biological evaluation of some novel 2-(5-substituted 1, 3, 4-oxadiazole-2-yl)-1, 3-benzothiazole Derivatives as Anticonvulsant …

SL Khokra, S Kaur, S Banwala… - … System Agents in …, 2021 - ingentaconnect.com
Background: Benzothiazole is an organosulfur heterocyclic compound that has a
considerable place in drug discovery due to significant pharmacological actions. Objective …

Synthesis and antibacterial evaluation of 1, 3-benzoxazepine-1, 5-diones bearing Benzothiazole moiety

ZH Abood, ZK Chafcheer… - Research Journal of …, 2021 - indianjournals.com
Azo-aldehyde derivative (2) was prepared through reaction of 2-hydroxybenzaldehyde with
diazonium ion generated from 2-aminobenzothiazole (1). The producing aldehyde (2) was …

Biological screening and structure activity relationship of benzothiazole

K Bhagdev, S Sarkar - Research Journal of Pharmacy and …, 2022 - indianjournals.com
Benzothiazole is a heterocyclic compound having nitrogen and sulphur. It's a bicyclic
compound with a thiazole with benzene ring fused together. As per a review of the literature …