Neural stem cells (NSCs) generate new neurons throughout life in the mammalian brain.
Adult-born neurons shape brain function, and endogenous NSCs could potentially be …

Adult hippocampal neurogenesis was originally discovered in rodents. Subsequent studies
identified the adult neural stem cells and found important links between adult neurogenesis …

Earlier observations in neuroscience suggested that no new neurons form in the mature
central nervous system. Evidence now indicates that new neurons do form in the adult …

Conflicting reports about whether adult hippocampal neurogenesis occurs in humans raise
questions about its significance for human health and the relevance of animal models …

The capability of the mammalian brain to generate new neurons through the lifespan has
gained much attention for the promise of new therapeutic possibilities especially for the …

Studies on brain plasticity have undertaken different roads, tackling a wide range of
biological processes: from small synaptic changes affecting the contacts among neurons at …

A theoretical framework is proposed to gain insight into the pathogenesis of major
depressive disorder (MDD). Despite being a relatively weak argument, the neurogenesis …

Two of the most common neurodegenerative disorders–Alzheimer's and Parkinson's
diseases–are characterized by synaptic dysfunction and degeneration that culminate in …

Plasticity, and in particular, neurogenesis, is a promising target to treat and prevent a wide
variety of diseases (eg, epilepsy, stroke, dementia). There are different types of plasticity …

During immature stages, adult-born neurons pass through critical periods for survival and
plasticity. It is generally assumed that by 2 months of age adult-born neurons are mature and …