Design of RNAs: comparing programs for inverse RNA folding

A Churkin, MD Retwitzer, V Reinharz… - Briefings in …, 2018 - academic.oup.com
Computational programs for predicting RNA sequences with desired folding properties have
been extensively developed and expanded in the past several years. Given a secondary …

Alternate RNA structures

MTP Wu, V D'Souza - Cold Spring Harbor Perspectives …, 2020 - cshperspectives.cshlp.org
SUMMARY RNA molecules fold into complex three-dimensional structures that sample
alternate conformations ranging from minor differences in tertiary structure dynamics to …

Riboswitch Scanner: an efficient pHMM-based web-server to detect riboswitches in genomic sequences

S Mukherjee, S Sengupta - Bioinformatics, 2016 - academic.oup.com
Riboswitches are non-coding RNA located in the 5′ untranslated regions where they bind
a target metabolite used to specify the riboswitch class and control the expression of …

An archaeal fluoride-responsive riboswitch provides an inducible expression system for hyperthermophiles

MC Speed, BW Burkhart, JW Picking… - Applied and …, 2018 - Am Soc Microbiol
Robust genetic systems for the hyperthermophilic Thermococcales have facilitated the
overexpression of native genes, enabled the addition of sequences encoding secretion …

A computational approach for the identification of distant homologs of bacterial riboswitches based on inverse RNA folding

S Mukherjee, MD Retwitzer, SM Hubbell… - Briefings in …, 2023 - academic.oup.com
Riboswitches are conserved structural ribonucleic acid (RNA) sensors that are mainly found
to regulate a large number of genes/operons in bacteria. Presently,> 50 bacterial riboswitch …

Phylogenomic and comparative analysis of the distribution and regulatory patterns of TPP riboswitches in fungi

S Mukherjee, MD Retwitzer, D Barash, S Sengupta - Scientific reports, 2018 - nature.com
Riboswitches are metabolite or ion sensing cis-regulatory elements that regulate the
expression of the associated genes involved in biosynthesis or transport of the …

incaRNAfbinv: a web server for the fragment-based design of RNA sequences

M Drory Retwitzer, V Reinharz, Y Ponty… - Nucleic acids …, 2016 - academic.oup.com
In recent years, new methods for computational RNA design have been developed and
applied to various problems in synthetic biology and nanotechnology. Lately, there is …

Comparative genomics and phylogenomic analyses of lysine riboswitch distributions in bacteria

S Mukherjee, D Barash, S Sengupta - PLoS One, 2017 - journals.plos.org
Riboswitches are cis-regulatory elements that regulate the expression of genes involved in
biosynthesis or transport of a ligand that binds to them. Among the nearly 40 classes of …

[HTML][HTML] The Bacillaceae-1 RNA motif comprises two distinct classes

E González-Tortuero, C Anthon, JH Havgaard… - Gene, 2022 - Elsevier
Non-coding RNAs are key regulatory players in bacteria. Many computationally predicted
non-coding RNAs, however, lack functional associations. An example is the Bacillaceae-1 …

incaRNAfbinv 2.0: a webserver and software with motif control for fragment-based design of RNAs

MD Retwitzer, V Reinharz, A Churkin, Y Ponty… - …, 2020 - academic.oup.com
RNA design has conceptually evolved from the inverse RNA folding problem. In the classical
inverse RNA problem, the user inputs an RNA secondary structure and receives an output …