Exercise as medicine in multiple sclerosis—time for a paradigm shift: preventive, symptomatic, and disease-modifying aspects and perspectives

U Dalgas, M Langeskov-Christensen… - Current neurology and …, 2019 - Springer
Abstract Purpose of Review For many years, exercise was controversial in multiple sclerosis
(MS) and thought to exacerbate symptoms and fatigue. However, having been found to be …

Treatment and management of cognitive dysfunction in patients with multiple sclerosis

J DeLuca, ND Chiaravalloti, BM Sandroff - Nature Reviews Neurology, 2020 - nature.com
Cognitive impairment is a common and devastating manifestation of multiple sclerosis (MS).
Although disease-modifying therapies have been efficacious for reducing relapse rates in …

Functional and/or structural brain changes in response to resistance exercises and resistance training lead to cognitive improvements–a systematic review

F Herold, A Törpel, L Schega, NG Müller - European Review of Aging and …, 2019 - Springer
Background During the aging process, physical capabilities (eg, muscular strength) and
cognitive functions (eg, memory) gradually decrease. Regarding cognitive functions …

[HTML][HTML] The impact of aerobic and resistance training intensity on markers of neuroplasticity in health and disease

T Hortobágyi, T Vetrovsky, GM Balbim… - Ageing Research …, 2022 - Elsevier
Objective To determine the effects of low-vs. high-intensity aerobic and resistance training
on motor and cognitive function, brain activation, brain structure, and neurochemical …

Exercise training for multiple sclerosis: a narrative review of history, benefits, safety, guidelines, and promotion

YC Learmonth, RW Motl - … journal of environmental research and public …, 2021 - mdpi.com
Background: There have been significant advances in the medical treatment and
management of multiple sclerosis pathogenesis, relapse and disease progression over the …

The effect of exercise on cognitive function in people with multiple sclerosis: A systematic review and meta-analysis of randomized controlled trials

G Li, Q You, X Hou, S Zhang, L Du, Y Lv, L Yu - Journal of neurology, 2023 - Springer
Objective A growing body of research examining the effect of exercise on cognitive function
in people with multiple sclerosis (MS), while findings of available studies were conflicting …

Fitness, physical activity, and exercise in multiple sclerosis: a systematic review on current evidence for interactions with disease activity and progression

S Proschinger, P Kuhwand, A Rademacher… - Journal of …, 2022 - Springer
Background A moderate to high level of physical activity, including regular exercise,
represents an established behavioral and rehabilitative approach for persons with multiple …

Exercise-induced increase in blood-based brain-derived neurotrophic factor (BDNF) in people with multiple sclerosis: A systematic review and meta-analysis of …

P Shobeiri, A Karimi, S Momtazmanesh, AL Teixeira… - PloS one, 2022 - journals.plos.org
Background Exercise training may affect the blood levels of brain-derived neurotrophic
factor (BDNF), but meta-analyses have not yet been performed comparing pre-and post …

Understanding lifestyle self-management regimens that improve the life quality of people living with multiple sclerosis: a systematic review and meta-analysis

OC Wills, YC Probst - Health and quality of life outcomes, 2022 - Springer
Background Lifestyle self-management as an intervention for people living with multiple
sclerosis (plwMS) is an emerging area of research. Previous reviews have highlighted a …

Efficacy of high-intensity aerobic exercise on brain MRI measures in multiple sclerosis

M Langeskov-Christensen, L Grøndahl Hvid… - Neurology, 2021 - AAN Enterprises
Objective To determine whether 24 weeks of high-intensity progressive aerobic exercise
(PAE) affects brain MRI measures in people with multiple sclerosis (MS). Methods We …