At least 3 million Americans sustain a mild traumatic brain injury (mTBI) each year, and 1 in
5 have symptoms that persist beyond 1 month. Standards of mTBI care have evolved rapidly …

Screening tests are widely used in medicine to assess the likelihood that members of a
defined population have a particular disease. This article presents an overview of such tests …

Classification techniques have been applied to many applications in various fields of
sciences. There are several ways of evaluating classification algorithms. The analysis of …

Animal testing is used in pharmaceutical and industrial research to predict human toxicity,
and yet analysis suggests that animal models are poor predictors of drug safety in humans …

Background Approximately 40% of pancreatic tumors smaller than 2 cm are missed at
abdominal CT. Purpose To develop and to validate a deep learning (DL)–based tool able to …

Background This publication represents a scheduled update of the 2019 guidelines of the
International Working Group of the Diabetic Foot (IWGDF) addressing the use of systems to …

The early and efficient assessment of cardiac safety liabilities is essential to confidently
advance novel drug candidates. This article discusses evolving mechanistically based …

Background: Thyroid nodules are a common finding in the general population, and their
detection is increasing with the widespread use of ultrasound (US). Thyroid cancer is found …

The field of machine learning has matured to the point where many sophisticated learning
approaches can be applied to practical applications. Thus it is of critical importance that …

Drug-induced liver injury (DILI) continues to be a major source of clinical attrition,
precautionary warnings, and post-market withdrawal of drugs. Accordingly, there is a need …