Mechanism of action of ribosomally synthesized and post-translationally modified peptides

C Ongpipattanakul, EK Desormeaux… - Chemical …, 2022 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Alkane oxidation: methane monooxygenases, related enzymes, and their biomimetics

VCC Wang, S Maji, PPY Chen, HK Lee, SSF Yu… - Chemical …, 2017 - ACS Publications
Methane monooxygenases (MMOs) mediate the facile conversion of methane into methanol
in methanotrophic bacteria with high efficiency under ambient conditions. Because the …

Copper active sites in biology

EI Solomon, DE Heppner, EM Johnston… - Chemical …, 2014 - ACS Publications
On the basis of its generally accessible I/II redox couple and bioavailability, copper plays a
wide variety of roles in nature that mostly involve electron transfer (ET), O 2 binding …

Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer

CW Koo, FJ Tucci, Y He, AC Rosenzweig - Science, 2022 - science.org
Bacterial methane oxidation using the enzyme particulate methane monooxygenase
(pMMO) contributes to the removal of environmental methane, a potent greenhouse gas …

Methane as a resource: can the methanotrophs add value?

PJ Strong, S Xie, WP Clarke - Environmental science & …, 2015 - ACS Publications
Methane is an abundant gas used in energy recovery systems, heating, and transport.
Methanotrophs are bacteria capable of using methane as their sole carbon source. Although …

Biochemistry of aerobic biological methane oxidation

CW Koo, AC Rosenzweig - Chemical Society Reviews, 2021 - pubs.rsc.org
Methanotrophic bacteria represent a potential route to methane utilization and mitigation of
methane emissions. In the first step of their metabolic pathway, aerobic methanotrophs use …

A tale of two methane monooxygenases

MO Ross, AC Rosenzweig - JBIC Journal of Biological Inorganic …, 2017 - Springer
Methane monooxygenase (MMO) enzymes activate O 2 for oxidation of methane. Two
distinct MMOs exist in nature, a soluble form that uses a diiron active site (sMMO) and a …

Enzymatic oxidation of methane

S Sirajuddin, AC Rosenzweig - Biochemistry, 2015 - ACS Publications
Methane monooxygenases (MMOs) are enzymes that catalyze the oxidation of methane to
methanol in methanotrophic bacteria. As potential targets for new gas-to-liquid methane …

Metabolic engineering in methanotrophic bacteria

MG Kalyuzhnaya, AW Puri, ME Lidstrom - Metabolic engineering, 2015 - Elsevier
Methane, as natural gas or biogas, is the least expensive source of carbon for (bio) chemical
synthesis. Scalable biological upgrading of this simple alkane to chemicals and fuels can …

Methanotrophs and copper

JD Semrau, AA DiSpirito, S Yoon - FEMS microbiology reviews, 2010 - academic.oup.com
Methanotrophs, cells that consume methane (CH4) as their sole source of carbon and
energy, play key roles in the global carbon cycle, including controlling anthropogenic and …