Transformative impact of proteomics on cardiovascular health and disease: a scientific statement from the American Heart Association
The year 2014 marked the 20th anniversary of the coining of the term proteomics. The
purpose of this scientific statement is to summarize advances over this period that have …
purpose of this scientific statement is to summarize advances over this period that have …
Clinical proteomic biomarkers: relevant issues on study design & technical considerations in biomarker development
Biomarker research is continuously expanding in the field of clinical proteomics. A
combination of different proteomic–based methodologies can be applied depending on the …
combination of different proteomic–based methodologies can be applied depending on the …
Integrated microfluidic devices for point-of-care detection of bio-analytes and disease
Micro-and nanofluidics have enabled the possibility of miniaturized analytical systems,
which are commonly known as lab-on-a-chip (LOC) devices. One of the clear benefits of …
which are commonly known as lab-on-a-chip (LOC) devices. One of the clear benefits of …
Homogeneous biosensing based on magnetic particle labels
The growing availability of biomarker panels for molecular diagnostics is leading to an
increasing need for fast and sensitive biosensing technologies that are applicable to point-of …
increasing need for fast and sensitive biosensing technologies that are applicable to point-of …
Ethical principles, constraints, and opportunities in clinical proteomics
Recent advances in MS-based proteomics have vastly increased the quality and scope of
biological information that can be derived from human samples. These advances have …
biological information that can be derived from human samples. These advances have …
Challenges in translational machine learning
A Couckuyt, R Seurinck, A Emmaneel, K Quintelier… - Human Genetics, 2022 - Springer
Abstract Machine learning (ML) algorithms are increasingly being used to help implement
clinical decision support systems. In this new field, we define as “translational machine …
clinical decision support systems. In this new field, we define as “translational machine …
Serum and urine biomarkers for human renal cell carcinoma
AL Pastore, G Palleschi, L Silvestri… - Disease …, 2015 - Wiley Online Library
Renal cell carcinoma (RCC) diagnosis is mostly achieved incidentally by imaging provided
for unrelated clinical reasons. The surgical management of localized tumors has reported …
for unrelated clinical reasons. The surgical management of localized tumors has reported …
Pitfalls in cutaneous melanoma diagnosis and the need for new reliable markers
Cutaneous melanoma is one of the most aggressive forms of skin cancer, with the
development of advanced stage disease resulting in a high rate of patient mortality. Accurate …
development of advanced stage disease resulting in a high rate of patient mortality. Accurate …
Placental pathology predicts infantile neurodevelopment
M Ueda, KJ Tsuchiya, C Yaguchi, N Furuta-Isomura… - Scientific Reports, 2022 - nature.com
The aim of present study was to investigate the association of placental pathological findings
with infantile neurodevelopment during the early 40 months of life. 258 singleton infants …
with infantile neurodevelopment during the early 40 months of life. 258 singleton infants …
Urine LOX-1 and volatilome as promising tools towards the early detection of renal cancer
M Murdocca, F Torino, S Pucci, M Costantini… - Cancers, 2021 - mdpi.com
Simple Summary Renal cell carcinoma (RCC) is often late diagnosed at an advanced stage,
worsening the prognosis of the patients. Thus, an early marker is desirable. This paper …
worsening the prognosis of the patients. Thus, an early marker is desirable. This paper …