Bridging from single to collective cell migration: A review of models and links to experiments

A Buttenschön, L Edelstein-Keshet - PLoS computational biology, 2020 - journals.plos.org
Mathematical and computational models can assist in gaining an understanding of cell
behavior at many levels of organization. Here, we review models in the literature that focus …

Effect of Porous Substrate Topographies on Cell Dynamics: A Computational Study

AR Gonthier, EL Botvinick, A Grosberg… - … Biomaterials Science & …, 2023 - ACS Publications
Controlling cell–substrate interactions via the microstructural characteristics of biomaterials
offers an advantageous path for modulating cell dynamics, mechanosensing, and migration …

Effect of geometric curvature on collective cell migration in tortuous microchannel devices

MB Mazalan, MAB Ramlan, JH Shin, T Ohashi - Micromachines, 2020 - mdpi.com
Collective cell migration is an essential phenomenon in many naturally occurring
pathophysiological processes, as well as in tissue engineering applications. Cells in tissues …

Force-mediated cellular anisotropy and plasticity dictate the elongation dynamics of embryos

C Fang, X Wei, X Shao, Y Lin - Science Advances, 2021 - science.org
We developed a unified dynamic model to explain how cellular anisotropy and plasticity,
induced by alignment and severing/rebundling of actin filaments, dictate the elongation …

Finite element analysis of the influence of cyclic strain on cells anchored to substrates with varying properties

A Banerjee, MP Khan, A Barui, P Datta… - Medical & Biological …, 2022 - Springer
The response of cytoskeleton to mechanical cues plays a pivotal role in understanding
several aspects of cellular growth, migration, and cell–cell and cell–matrix interactions under …

A formalism for modelling traction forces and cell shape evolution during cell migration in various biomedical processes

Q Peng, FJ Vermolen, D Weihs - Biomechanics and Modeling in …, 2021 - Springer
The phenomenological model for cell shape deformation and cell migration Chen (BMM 17:
1429–1450, 2018), Vermolen and Gefen (BMM 12: 301–323, 2012), is extended with the …

[HTML][HTML] Physical confinement and cell proximity increase cell migration rates and invasiveness: A mathematical model of cancer cell invasion through flexible …

Q Peng, FJ Vermolen, D Weihs - journal of the mechanical behavior of …, 2023 - Elsevier
Cancer cell migration between different body parts is the driving force behind cancer
metastasis, which is the main cause of mortality of patients. Migration of cancer cells often …

Quantification of tumorsphere migration with a physics‐based machine learning method

CK Vong, A Wang, M Dragunow, TIH Park… - Cytometry Part …, 2023 - Wiley Online Library
Current analysis techniques available for migration assays only provide quantitative
measurements for overall migration. However, the potential of regional migration analyses …

A methylation diagnostic model based on random forests and neural networks for asthma identification

DD Li, T Chen, YL Ling, YA Jiang… - … Mathematical Methods in …, 2022 - Wiley Online Library
Background. Asthma significantly impacts human life and health as a chronic disease.
Traditional treatments for asthma have several limitations. Artificial intelligence aids in …

Effect of geometric curvature on collective cell migration in tortuous microchannel devices

M Bin Mazalan, MA Bin Ramlan, JH Shin… - …, 2020 - koasas.kaist.ac.kr
Collective cell migration is an essential phenomenon in many naturally occurring
pathophysiological processes, as well as in tissue engineering applications. Cells in tissues …