Although much research has been done on the diversity of the gut microbiome, little is
known about how it influences intestinal homeostasis under normal and pathogenic …

Abstract TET2/3 play a well-known role in epigenetic regulation and mouse development.
However, their function in cellular differentiation and tissue homeostasis remains poorly …

The uterus is vital for successful reproduction in mammals, and two different types of
epithelia (luminal and glandular) are essential for embryo implantation and pregnancy …

So far, the understanding of germ cell cancer (GCC) pathogenesis is based on a model,
where seminomas and non‐seminomas represent distinct entities although originating from …

Esophageal adenocarcinoma (EAC) is one of the most frequent causes of cancer death, and
yet compared to other common cancers, we know relatively little about the molecular …

Background The epithelial lining of the human epididymis is critical for sperm maturation.
This process requires distinct specialized functions in the head, body, and tail of the duct …

Higher order chromatin structure establishes domains that organize the genome and
coordinate gene expression. However, the molecular mechanisms controlling transcription …

FOXA2, a member of the forkhead family of transcription factors, plays essential roles in liver
development and bile acid homeostasis. In this study, we report a 2.8 Å co-crystal structure …

The differentiated functions of the human airway epithelium are coordinated by a complex
network of transcription factors. These include the pioneer factors Forkhead box A1 and A2 …

SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal
carcinoma-like fate - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …