Organic fluorescent probes for monitoring autophagy in living cells
X Li, X Liang, J Yin, W Lin - Chemical Society Reviews, 2021 - pubs.rsc.org
As a ubiquitous degradation process in cells, autophagy plays important roles in various
biological activities. However, the abnormality of autophagy is closely related to many …
biological activities. However, the abnormality of autophagy is closely related to many …
[HTML][HTML] Breast cancer brain metastasis: insight into molecular mechanisms and therapeutic strategies
Y Wang, F Ye, Y Liang, Q Yang - British journal of cancer, 2021 - nature.com
Breast cancer is one of the most prevalent malignancies in women worldwide. Early-stage
breast cancer is considered a curable disease; however, once distant metastasis occurs, the …
breast cancer is considered a curable disease; however, once distant metastasis occurs, the …
Metastatic outgrowth via the two-way interplay of autophagy and metabolism
AB Behrooz, M Cordani, M Donadelli… - Biochimica et Biophysica …, 2023 - Elsevier
Metastasis represents one of the most dangerous issue of cancer progression, characterized
by intricate interactions between invading tumor cells, various proteins, and other cells on …
by intricate interactions between invading tumor cells, various proteins, and other cells on …
Biomimetic lipopolysaccharide‐free bacterial outer membrane‐functionalized nanoparticles for brain‐targeted drug delivery
H Chen, M Zhou, Y Zeng, T Miao, H Luo… - Advanced …, 2022 - Wiley Online Library
The blood–brain barrier (BBB) severely blocks the intracranial accumulation of most
systemic drugs. Inspired by the contribution of the bacterial outer membrane to Escherichia …
systemic drugs. Inspired by the contribution of the bacterial outer membrane to Escherichia …
Pan-and isoform-specific inhibition of Hsp90: Design strategy and recent advances
J Yu, C Zhang, C Song - European Journal of Medicinal Chemistry, 2022 - Elsevier
In the past few decades, the development of heat shock protein 90 (Hsp90) inhibitors for
cancer treatment has not stopped. About twenty compounds have been evaluated in the …
cancer treatment has not stopped. About twenty compounds have been evaluated in the …
[HTML][HTML] Molecular chaperone GRP94/GP96 in cancers: oncogenesis and therapeutic target
X Duan, S Iwanowycz, S Ngoi, M Hill, Q Zhao… - Frontiers in …, 2021 - frontiersin.org
During tumor development and progression, intrinsic and extrinsic factors trigger
endoplasmic reticulum (ER) stress and the unfolded protein response, resulting in the …
endoplasmic reticulum (ER) stress and the unfolded protein response, resulting in the …
The biology and inhibition of glucose‐regulated protein 94/gp96
KW Pugh, M Alnaed, CM Brackett… - Medicinal research …, 2022 - Wiley Online Library
The 94 kDa molecular chaperone, glucose‐regulated protein 94 (Grp94), has garnered
interest during the last decade due to its direct association with endoplasmic reticulum (ER) …
interest during the last decade due to its direct association with endoplasmic reticulum (ER) …
DH5α Outer Membrane‐Coated Biomimetic Nanocapsules Deliver Drugs to Brain Metastases but not Normal Brain Cells via Targeting GRP94
M Zhou, H Chen, Y Zeng, Z Lv, X Hu, Y Tong, P Wang… - Small, 2023 - Wiley Online Library
Receptor‐mediated vesicular transport has been extensively developed to penetrate the
blood‐brain barrier (BBB) and has emerged as a class of powerful brain‐targeting delivery …
blood‐brain barrier (BBB) and has emerged as a class of powerful brain‐targeting delivery …
[HTML][HTML] Towards dual function of autophagy in breast cancer: A potent regulator of tumor progression and therapy response
M Hashemi, MDA Paskeh, S Orouei, P Abbasi… - Biomedicine & …, 2023 - Elsevier
As a devastating disease, breast cancer has been responsible for decrease in life
expectancy of females and its morbidity and mortality are high. Breast cancer is the most …
expectancy of females and its morbidity and mortality are high. Breast cancer is the most …
[HTML][HTML] Autophagy-mediated tumor cell survival and progression of breast cancer metastasis to the brain
A Maiti, NC Hait - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Brain metastases represent a substantial amount of morbidity and mortality in breast cancer
(BC). Metastatic breast tumor cells committed to brain metastases are unique because they …
(BC). Metastatic breast tumor cells committed to brain metastases are unique because they …