Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

Evidence suggests that the perioperative period and the excision of the primary tumour can
promote the development of metastases—the main cause of cancer-related mortality. This …

Debate on appropriate triggers for transfusion of allogeneic blood products and their effects
on short-and long-term survival in surgical and critically ill patients continue with no …

Surgery is an important treatment modality for the majority of solid organ cancers.
Unfortunately, cancer recurrence following surgery of curative intent is common, and …

A wealth of basic science data supports the hypothesis that the surgical stress response
increases the likelihood of cancer dissemination and metastasis during and after cancer …

Surgery for the removal of a primary tumor presents an opportunity to eradicate cancer or
arrest its progression, but is also believed to promote the outbreak of pre-existing …

Whether blood transfusion exacerbates cancer outcomes after surgery in humans remains
inconclusive. We utilized a large cohort to investigate the effect of perioperative blood …

Clinical practice does not consider perioperative paracrine and neuroendocrine stress
responses as risk factors for cancer recurrence, although recent animal studies provided …

Transfusion‐related immunomodulation (TRIM) in the intensive care unit (ICU) is difficult to
define and likely represents a complicated set of physiologic responses to transfusion …

Transfusion-related immunomodulation: a reappraisal : Current Opinion in Hematology
Transfusion-related immunomodulation: a reappraisal : Current Opinion in Hematology Log …