Application of smart nanoparticles as a potential platform for effective colorectal cancer therapy

S Iranpour, AR Bahrami, AS Saljooghi… - Coordination Chemistry …, 2021 - Elsevier
Nowadays, nanomedicine has emerged as one of the most interesting fields of biomedical
research, combining nanotechnology and medicine to offer a better prospect to design …

Synthesis of a targeted, dual pH and redox-responsive nanoscale coordination polymer theranostic against metastatic breast cancer in vitro and in vivo

M Falsafi, N Hassanzadeh Goji… - Expert Opinion on …, 2022 - Taylor & Francis
Background Nanoscale coordination polymers (nCP) have exhibited a great potential in
designing of the theranostic platforms in the latest years. However, they have low selectivity …

[HTML][HTML] Hybrid system for local drug delivery and magnetic hyperthermia based on SPIONs loaded with doxorubicin and epirubicin

D Nieciecka, J Celej, M Żuk, A Majkowska-Pilip… - Pharmaceutics, 2021 - mdpi.com
Cancer is one of the most common causes of death worldwide, thus new solutions in
anticancer therapies are highly sought after. In this work, superparamagnetic iron oxide …

[HTML][HTML] Targeted SPION siderophore conjugate loaded with doxorubicin as a theranostic agent for imaging and treatment of colon carcinoma

R Nosrati, K Abnous, M Alibolandi, J Mosafer… - Scientific Reports, 2021 - nature.com
Recently, the siderophores have opened new horizons in nanomedicine. The current study
aimed to design a theranostic platform based on superparamagnetic iron oxide …

PlasmaDerived Nanoclusters for SiteSpecific Multimodality Photo/Magnetic Thrombus Theranostics

CH Liu, MC Liu, PR Jheng, J Yu, YJ Fan… - Advanced …, 2023 - Wiley Online Library
Traditional thrombolytic therapeutics for vascular blockage are affected by their limited
penetration into thrombi, associated offtarget side effects, and low bioavailability, leading to …

Iron Oxide Nanoparticles: The precise strategy for targeted delivery of genes, oligonucleotides and peptides in cancer therapy

V Sachdeva, A Monga, R Vashisht, D Singh… - Journal of Drug Delivery …, 2022 - Elsevier
The advent of diagnostic and therapeutic agents in lieu of enhancing the specificity towards
tumors has brought genes, oligonucleotides and peptides to the forefront. Optimal carrier …

Aptamers functionalized biomolecular nano-vehicles for applications in cancer diagnostics & therapeutics

S Das, A Gupta, TV Vaishnavi, S Walia… - Applied …, 2022 - pubs.thesciencein.org
Given its structural versatility and functional programmability, DNA has emerged as an ideal
scaffold for developing nanoscale materials with emerging applications, including the ones …

[HTML][HTML] Aptamer applications in emerging viral diseases

A Krüger, AP de Jesus Santos, V de Sá, H Ulrich… - Pharmaceuticals, 2021 - mdpi.com
Aptamers are single-stranded DNA or RNA molecules which are submitted to a process
denominated SELEX. SELEX uses reiterative screening of a random oligonucleotide library …

[HTML][HTML] Aptamers used for molecular imaging and theranostics-recent developments

L Bohrmann, T Burghardt, C Haynes, K Saatchi… - Theranostics, 2022 - ncbi.nlm.nih.gov
Aptamers are single stranded oligonucleotides that fold into three dimensional structures
and are able to recognize a variety of molecular targets. Due to the similarity to antibodies …

Synthesis of manganese-incorporated polycaplactone-poly (glyceryl methacrylate) theranostic smart hybrid polymersomes for efficient colon adenocarcinoma …

M Babaei, K Abnous, S Nekooei, SM Taghdisi… - International Journal of …, 2022 - Elsevier
In the current study, a multifunctional nanoscale vesicular system (polymersome) with the
ability to accumulate in the site of action, control drug release and integrate diagnostic and …