Introduction Sepsis biomarkers can have important diagnostic, therapeutic, and prognostic
functions. In a previous review, we identified 3370 references reporting on 178 different …

Introduction Biomarkers can be useful for identifying or ruling out sepsis, identifying patients
who may benefit from specific therapies or assessing the response to therapy. Methods We …

Sepsis represents the host's systemic inflammatory response to a severe infection. It causes
substantial human morbidity resulting in hundreds of thousands of deaths each year …

Neonatal sepsis is associated with severe morbidity and mortality in the neonatal period.
Clinical manifestations range from subclinical infection to severe local or systemic infection …

The fetus and newborn face a complex set of immunological demands, including protection
against infection, avoidance of harmful inflammatory immune responses that can lead to pre …

During foetal development, neonatal period and childhood, the immune system is constantly
maturing. In the foetus, infection responsiveness is low and associates with spontaneous …

Conventional methods utilized for clinical diagnosis of gastrointestinal (GI) diseases have
employed invasive medical procedures that cause stress, anxiety and pain to patients …

Sepsis or serious infection within the first 4 weeks of life kills more than 1 million newborns
globally every year. 1 The attack rate for neonatal sepsis is variable (from< 1% to> 35% of …

As neonatal sepsis is a severe condition, there is a call for reliable biomarkers to
differentiate between infected and noninfected newborns. Although blood culture has been …

Neonatal sepsis, a clinical disorder developed by bacterial blood stream infections (BSI) in
neonates, is one of the serious global public health problems that must be addressed. More …