STRUCTURE OF PROTEIN GPI ANCHORS Although some of the plasma membrane
proteins of the parasitic protozoa use transmembrane polypeptide anchors, most of the …

▪ Abstract Leishmania-sand fly interactions are reviewed in the context of the potential
barriers to the complete development of the parasite that exist within the midgut environment …

Leishmania sp. are digenetic protozoa that cause an estimated 1.5–2 million new cases of
leishmaniasis per year worldwide. Among the molecular factors that contribute to …

Leishmania species are obligate intracellular parasites of cells of the macrophage-dendritic
cell lineage. Indeed, the ability to survive and multiply within macrophages is a feature of a …

Leishmania are a resilient group of intracellular parasites that infect macrophages. The
resultant complex of diseases, or leishmaniases, caused by the parasites affect over twelve …

Publisher Summary Although there are several reports of Leishmania parasitizing cells other
than macrophages or even existing extracellularly in mammalian tissue, it is generally …

Protozoan parasites of the genus Leishmania produce the novel surface glycoconjugate,
lipophosphoglycan (LPG), which is required for parasite infectivity. In this study we show that …

Although leishmaniasis is transmitted to humans almost exclusively by the bite of infected
phlebotomine sandflies, little is known about the molecules controlling the survival and …

Leishmania promastigotes synthesize an abundance of phosphoglycans, either attached to
the cell surface through phosphatidylinositol anchors (lipophosphoglycan, LPG) or secreted …

In addition to utilizing glycosylated phosphatidylinositols (GPIs) as anchors for surface
proteins, protozoan parasites of the genus Leishmania synthesize two novel classes of GPI …