Cell-matrix interactions play a critical role in tissue repair and regeneration. With gradual
uncovering of substrate mechanical characteristics that can affect cell-matrix interactions …

Polysaccharides and proteins are important macromolecules for developing hydrogels
devoted to biomedical applications. Chemical hydrogels offer chemical, mechanical, and …

Human pluripotent stem cells have emerged as a promising in vitro model system for
studying the brain. Two-dimensional and three-dimensional cell culture paradigms have …

Biodegradable polymers play a pivotal role in in situ tissue engineering. Utilizing various
technologies, researchers have been able to fabricate 3D tissue engineering scaffolds using …

The treatment of long-gap (> 10 mm) peripheral nerve injury (PNI) and spinal cord injury
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …

Peripheral nerve injury (PNI), one of the most common concerns following trauma, can result
in a significant loss of sensory or motor function. Restoration of the injured nerves requires a …

Hydrogel materials have been employed as biological scaffolds for tissue regeneration
across a wide range of applications. Their versatility and biomimetic properties make them …

The cross-talk between stem cells and their microenvironment has been shown to have a
direct impact on stem cells' decisions about proliferation, growth, migration, and …

Since the advent of organ-on-a-chip, many researchers have tried to mimic the physiology of
human tissue on an engineered platform. In the case of brain tissue, structural connections …

Graphene has made significant contributions to neural tissue engineering due to its
electrical conductivity, biocompatibility, mechanical strength, and high surface area …