Circular RNAs in body fluids as cancer biomarkers: the new frontier of liquid biopsies

S Wang, K Zhang, S Tan, J Xin, Q Yuan, H Xu, X Xu… - Molecular cancer, 2021 - Springer
Cancer is a leading cause of death worldwide, particularly because of its high mortality rate
in patients who are diagnosed at late stages. Conventional biomarkers originating from …

[HTML][HTML] Bioinspired surfaces with wettability: biomolecule adhesion behaviors

H Fan, Z Guo - Biomaterials science, 2020 - pubs.rsc.org
Surface wettability plays an important role in regulating biomolecule adhesion behaviors.
The biomolecule adhesion behaviors of superwettable surfaces have become an important …

Current advances of liquid biopsies in prostate cancer: Molecular biomarkers

M Alahdal, RA Perera, MC Moschovas, V Patel… - Molecular Therapy …, 2023 - cell.com
Prostate cancer (PCa) incidence is increasing and endangers men's lives. Early detection of
PCa could improve overall survival (OS) by preventing metastasis. The prostate-specific …

Liquid biopsy on the horizon in immunotherapy of non-small cell lung cancer: current status, challenges, and perspectives

Y Yang, H Liu, Y Chen, N Xiao, Z Zheng, H Liu… - Cell Death & …, 2023 - nature.com
Non-small cell lung cancer (NSCLC) is one of the most threatening malignancies to human
health and life. In most cases, patients with NSCLC are already at an advanced stage when …

[HTML][HTML] Precision oncology in the age of integrative genomics

C Kumar-Sinha, AM Chinnaiyan - Nature biotechnology, 2018 - nature.com
Precision oncology applies genomic and other molecular analyses of tumor biopsies to
improve the diagnosis and treatment of cancers. In addition to identifying therapeutic …

Live single cell mass spectrometry reveals cancer‐specific metabolic profiles of circulating tumor cells

Y Abouleila, K Onidani, A Ali, H Shoji, T Kawai… - Cancer …, 2019 - Wiley Online Library
Recently, there has been increased attention on the analysis of circulating tumor cells (CTC
s), also known as liquid biopsy, owing to its potential benefits in cancer diagnosis and …

Hydrogel-based biosensors

K Völlmecke, R Afroz, S Bierbach, LJ Brenker, S Frücht… - Gels, 2022 - mdpi.com
There is an increasing interest in sensing applications for a variety of analytes in aqueous
environments, as conventional methods do not work reliably under humid conditions or they …

Polyethylene glycol improves current methods for circulating extracellular vesicle-derived DNA isolation

N García-Romero, R Madurga, G Rackov… - Journal of translational …, 2019 - Springer
Abstract Background Extracellular vesicles (EVs) are small membrane-bound vesicles which
play an important role in cell-to-cell communication. Their molecular cargo analysis is …

[PDF][PDF] On the concepts and history of glioblastoma multiforme—morphology, genetics and epigenetics

GS Stoyanov, DL Dzhenkov - Folia Med, 2018 - researchgate.net
The knowledge of GBM has been closely related to general medical knowledge of the CNS
since these malignancies were first described more than 200 years ago. Several great leaps …

Circulating nucleosomes and nucleosome modifications as biomarkers in cancer

P McAnena, JAL Brown, MJ Kerin - Cancers, 2017 - mdpi.com
Traditionally the stratification of many cancers involves combining tumour and
clinicopathological features (eg, patient age; tumour size, grade, receptor status and …