Osteoarthritis (OA) is a musculoskeletal disease characterized by progressive degeneration
of osteochondral tissues. Current treatment is restricted to the reduction of pain and loss of …

Osteoarthritis (OA), characterized by chondrocyte apoptosis and disturbance of the balance
between catabolism and anabolism of the extracellular matrix (ECM), is the most common …

Recently, mesenchymal stem/stromal cells (MSCs) transplantation has been introduced as a
promising option to support cartilage structure and improve its function in preclinical models …

Strontium (Sr) has shown strong osteogenic potential and thereby been widely incorporated
into dental and orthopedic implants. However, the improved osseointegration of strontium …

In the present study, alginate/cartilage extracellular matrix (ECM)-based injectable hydrogel
was developed incorporated with silk fibroin nanofibers (SFN) for cartilage tissue …

Numerous therapeutic strategies have been developed for osteoarthritis (OA) management,
including intra-articular (IA) injections. The ideal IA formulation should control cartilage …

Bioceramic scaffolds are crucial in tissue engineering for bone regeneration. They usually
provide hierarchical porosity, bioactivity, and mechanical support supplying osteoconductive …

Stem cells hold great potential in tissue engineering due to their prolonged self-renewal and
ability to differentiate into a variety of cell lines. Leveraging stem cells in regenerative …

Factors and molecules secreted by mesenchymal stem cells (MSCs) can be termed as
“secretome.” The MSC-derived secretome includes growth factors, cytokines, chemokines …

The immunomodulatory capacity of the human mesenchymal stromal cell (MSC) secretome
has been a critical driver for the development of cell-free MSC products, such as conditioned …