[图书][B] Epilepsy: a public health imperative

World Health Organization - 2019 - apps.who.int
Epilepsy is a brain disease characterized by abnormal electrical activity causing seizures or
unusual behaviour, sensations and sometimes loss of awareness. It carries neurological …

Effects of single cage housing on stress, cognitive, and seizure parameters in the rat and mouse pilocarpine models of epilepsy

H Manouze, A Ghestem, V Poillerat, M Bennis… - Eneuro, 2019 - eneuro.org
Many experimental approaches require housing rodents in individual cages, including in
epilepsy research. However, rats and mice are social animals; and individual housing …

Brain pathology in focal status epilepticus: evidence from experimental models

M de Curtis, AO Rossetti, DV Verde, EA van Vliet… - Neuroscience & …, 2021 - Elsevier
Status Epilepticus (SE) is often a neurological emergency characterized by abnormally
sustained, longer than habitual seizures. The new ILAE classification reports that SE “… can …

Classification of focal and non-focal epileptic patients using single channel EEG and long short-term memory learning system

L Fraiwan, M Alkhodari - IEEE Access, 2020 - ieeexplore.ieee.org
The process of inspecting electroencephalography (EEG) signals of patients with epilepsy to
distinguish between focal and non-focal seizure source is a crucial step prior to surgical …

Susceptibility to epilepsy after traumatic brain injury is associated with preexistent gut microbiome profile

JS Medel‐Matus, V Lagishetty, C Santana‐Gomez… - …, 2022 - Wiley Online Library
Objective We examined whether posttraumatic epilepsy (PTE) is associated with
measurable perturbations in gut microbiome. Methods Adult Sprague Dawley rats were …

Disruption of intestinal barrier and endotoxemia after traumatic brain injury: implications for post‐traumatic epilepsy

A Mazarati, JS Medel‐Matus, D Shin, JP Jacobs… - …, 2021 - Wiley Online Library
Objective Traumatic brain injury (TBI) may lead to the disruption of the intestinal barrier (IB),
and to the escape of products of commensal gut bacteria, including lipopolysaccharide …

A companion to the preclinical common data elements on neurobehavioral comorbidities of epilepsy: a report of the TASK 3 behavior working group of the ILAE/AES …

A Mazarati, NC Jones, AS Galanopoulou… - Epilepsia …, 2018 - Wiley Online Library
The provided companion has been developed by the Behavioral Working Group of the Joint
Translational Task Force of the International League Against Epilepsy (ILAE) and the …

Antiepileptogenesis and disease modification: Progress, challenges, and the path forward—Report of the Preclinical Working Group of the 2018 NINDS‐sponsored …

AS Galanopoulou, W Löscher, L Lubbers… - Epilepsia …, 2021 - Wiley Online Library
Epilepsy is one of the most common chronic brain diseases and is often associated with
cognitive, behavioral, or other medical conditions. The need for therapies that would …

Modification of post-traumatic epilepsy by fecal microbiota transfer

JS Medel-Matus, CA Simpson, AI Ahdoot, D Shin… - Epilepsy & Behavior, 2022 - Elsevier
It has been well established that traumatic brain injury (TBI) modifies the composition of gut
microbiome. Epilepsy, which represents one of the common sequelae of TBI, has been …

Common data elements (CDEs) for preclinical epilepsy research: Introduction to CDEs and description of core CDEs. A TASK3 report of the ILAE/AES joint …

LC Harte‐Hargrove, AS Galanopoulou… - Epilepsia …, 2018 - Wiley Online Library
Common data elements (CDEs) are becoming more common as more areas of preclinical
research have generated CDEs. Herein we provide an overview of the progress to date in …