Efficient saccharification of lignocellulosic biomass requires concerted development of a
pretreatment method, an enzyme cocktail and an enzymatic process, all of which are …

Biomass constitutes an appealing alternative to fossil resources for the production of
materials and energy. The abundance and attractiveness of vegetal biomass come along …

Enzymes currently known as lytic polysaccharide monooxygenases (LPMOs) play an
important role in the conversion of recalcitrant polysaccharides, but their mode of action has …

Fungi produce heme-containing peroxidases and peroxygenases, flavin-containing
oxidases and dehydrogenases, and different copper-containing oxidoreductases involved in …

The discovery of oxidative cleavage of glycosidic bonds by enzymes currently known as lytic
polysaccharide monooxygenases (LPMOs) has profoundly changed our current …

The discovery of lytic polysaccharide monooxygenases (LPMOs) has revolutionized
enzymatic processing of polysaccharides, in particular, recalcitrant insoluble …

Lytic polysaccharide monooxygenases (LPMOs) are abundant in nature and best known for
their role in the enzymatic conversion of recalcitrant polysaccharides such as chitin and …

Highlights•LPMOs show large structural and sequence variability that affect substrate-
interaction surfaces.•First X-ray crystallographic data on cellulose binding.•Large modular …

Natural carbohydrate polymers such as starch, cellulose, and chitin provide renewable
alternatives to fossil fuels as a source for fuels and materials. As such, there is considerable …

Highlights•Lytic polysaccharide monooxygenases (LPMOs) are abundant in nature and of
great biotechnological interest.•Substrate binding affects the catalytic competence of the …