[HTML][HTML] Preeclampsia: from cellular wellness to inappropriate cell death, and the roles of nutrition

AW Lokeswara, R Hiksas, R Irwinda… - Frontiers in Cell and …, 2021 - frontiersin.org
Preeclampsia is one of the most common obstetrical complications worldwide. The
pathomechanism of this disease begins with abnormal placentation in early pregnancy …

[HTML][HTML] Cadmium handling, toxicity and molecular targets involved during pregnancy: lessons from experimental models

T Jacobo-Estrada, M Santoyo-Sánchez… - International journal of …, 2017 - mdpi.com
Even decades after the discovery of Cadmium (Cd) toxicity, research on this heavy metal is
still a hot topic in scientific literature: as we wrote this review, more than 1440 scientific …

Global association between atmospheric particulate matter and obesity: a systematic review and meta-analysis

L Lin, T Li, M Sun, Q Liang, Y Ma, F Wang, J Duan… - Environmental …, 2022 - Elsevier
Background Among various air pollutants, particulate matter (PM) is the most harmful and
representative pollutant. Although several studies have shown a link between particulate …

[HTML][HTML] Surface-functionalized nanoparticles as efficient tools in targeted therapy of pregnancy complications

B Zhang, R Liang, M Zheng, L Cai, X Fan - International Journal of …, 2019 - mdpi.com
Minimizing exposure of the fetus to medication and reducing adverse off-target effects in the
mother are the primary challenges in developing novel drugs to treat pregnancy …

Exposome and foetoplacental vascular dysfunction in gestational diabetes mellitus

P Valero, G Fuentes, M Cornejo, S Vega… - Molecular Aspects of …, 2022 - Elsevier
A balanced communication between the mother, placenta and foetus is crucial to reach a
successful pregnancy. Several windows of exposure to environmental toxins are present …

Intrauterine multi-metal exposure is associated with reduced fetal growth through modulation of the placental gene network

MA Deyssenroth, C Gennings, SH Liu, S Peng… - Environment …, 2018 - Elsevier
Background Intrauterine metal exposures and aberrations in placental processes are known
contributors to being born small for gestational age (SGA). However, studies to date have …

Protective role of the placental efflux transporter BCRP/ABCG2 in the relationship between prenatal cadmium exposure, placenta weight, and size at birth

ES Barrett, Z Rivera-Núñez, K Getz… - Environmental …, 2023 - Elsevier
Background and aim Placental efflux transporter proteins, such as BCRP, reduce the
placental and fetal toxicity of environmental contaminants but have received little attention in …

[HTML][HTML] The effects of the exposure to neurotoxic elements on Italian schoolchildren behavior

S Renzetti, G Cagna, S Calza, M Conversano… - Scientific reports, 2021 - nature.com
Neurodevelopmental disorders are constantly increasing on a global scale. Some elements
like heavy metals are known to be neurotoxic. In this cross-sectional study we assessed the …

[HTML][HTML] Gene variants determine placental transfer of perfluoroalkyl substances (PFAS), mercury (Hg) and lead (Pb), and birth outcome: findings from the UmMuKi …

C Gundacker, K Graf-Rohrmeister, M Gencik… - Frontiers in …, 2021 - frontiersin.org
Prenatal exposure to perfluoroalkyl substances (PFAS), bisphenol A (BPA), lead (Pb), total
mercury (THg), and methylmercury (MeHg) can affect fetal development. Factors influencing …

[HTML][HTML] Amino acid transporter LAT1 (SLC7A5) mediates MeHg-induced oxidative stress defense in the human placental cell line HTR-8/SVneo

S Granitzer, R Widhalm, M Forsthuber… - International journal of …, 2021 - mdpi.com
The placental barrier can protect the fetus from contact with harmful substances. The potent
neurotoxin methylmercury (MeHg), however, is very efficiently transported across the …