Patients with systemic lupus erythematosus (SLE) frequently show symptoms of central
nervous system (CNS) involvement, termed neuropsychiatric SLE (NPSLE). The CNS …

B cells are essential components of the adaptive immune system and have important roles
in the pathogenesis of several central nervous system (CNS) diseases. Besides producing …

Background Pharmacological prevention against relapses in patients with neuromyelitis
optica spectrum disorder (NMOSD) is developing rapidly. We aimed to investigate the safety …

Background A subset of patients with neuromyelitis optica spectrum disorders (NMOSD) has
been shown to be seropositive for myelin oligodendrocyte glycoprotein antibodies (MOG …

Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory CNS disease that
primarily manifests as relapsing episodes of severe optic neuritis and myelitis. Diagnosis of …

Introduction Severe attacks of neuromyelitis optica spectrum disorder (NMO-SD) are
improved by plasma exchange (PLEX) given as an adjunctive therapy. Initial studies failed …

Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …

The understanding of neuromyelitis optica spectrum disorder (NMOSD) has evolved
substantially since its initial description over a century ago. The discovery in 2004 of a …

Neuromyelitis optica (NMO, Devic's syndrome), long considered a clinical variant of multiple
sclerosis, is now regarded as a distinct disease entity. Major progress has been made in the …

Background Neuromyelitis optica spectrum disorder is an autoimmune disease of the CNS
that primarily affects the optic nerves and spinal cord. Most patients have serum antibodies …