p‐Coumaric acid and its conjugates: dietary sources, pharmacokinetic properties and biological activities

K Pei, J Ou, J Huang, S Ou - Journal of the Science of Food and …, 2016 - Wiley Online Library
Abstract p‐Coumaric acid (4‐hydroxycinnamic acid) is a phenolic acid that has low toxicity in
mice (LD50= 2850 mg kg− 1 body weight), serves as a precursor of other phenolic …

Interactions between starch and phenolic compound

F Zhu - Trends in Food Science & Technology, 2015 - Elsevier
Highlights•Nature of starch-phenolics non-covalent interactions reviewed.•Interactions affect
physicochemical properties of starch and phenolics.•How to better utilise the interactions for …

Inhibitory mechanism of two allosteric inhibitors, oleanolic acid and ursolic acid on α-glucosidase

H Ding, X Hu, X Xu, G Zhang, D Gong - International journal of biological …, 2018 - Elsevier
Glycemic control which can be efficaciously regulated by inhibiting α-glucosidase activity is
an effective therapy for diabetes mellitus. This work is to investigate the kinetics and …

Synthesis of novel inhibitors of α-glucosidase based on the benzothiazole skeleton containing benzohydrazide moiety and their molecular docking studies

M Taha, NH Ismail, S Lalani, MQ Fatmi… - European journal of …, 2015 - Elsevier
In an effort to design and synthesize a new class of α-glucosidase inhibitor, we synthesized
benzothiazole hybrid having benzohydrazide moiety (5). Compound 5 was reacted with …

p-Coumaric Acid: A Naturally Occurring Chemical with Potential Therapeutic Applications

J Kaur, R Kaur - Current Organic Chemistry, 2022 - benthamdirect.com
Coumaric acid is a hydroxy derivative of cinnamic acid with three different isomers (ortho,
meta and para). Its most commonly available form is p-coumaric acid. p-Coumaric acid ie, 4 …

Triterpenic Acids as Non-Competitive α-Glucosidase Inhibitors from Boswellia elongata with Structure-Activity Relationship: In Vitro and In Silico Studies

N Ur Rehman, SA Halim, M Al-Azri, M Khan, A Khan… - Biomolecules, 2020 - mdpi.com
Fourteen triterpene acids, viz., three tirucallane-type (1–3), eight ursane-type (4–11), two
oleanane-type (12, 13) and one lupane type (21), along with boswellic aldehyde (14), α …

Inhibition of glycosidase by ursolic acid: in vitro, in vivo and in silico study

J Wang, J Zhao, Y Yan, D Liu, C Wang… - Journal of the Science …, 2020 - Wiley Online Library
BACKGROUND Controlling the blood glucose level is an effective method to reduce type 2
diabetes and prevent diabetes‐related complications. Ursolic acid is a plant extract that can …

Oligomeric proanthocyanidins are the active compounds in Abelmoschus esculentus Moench for its α-amylase and α-glucosidase inhibition activity

Y Lu, MF Demleitner, L Song, M Rychlik… - Journal of functional …, 2016 - Elsevier
We found that Abelmoschus esculentus Moench (okra, or lady's finger) exhibits significant α-
amylase and α-glucosidase inhibitory activity. Assay-guided fractionation of the okra extracts …

In Silico Molecular Docking and In Vitro Antidiabetic Studies of Dihydropyrimido[4,5‐a]acridin‐2‐amines

A Bharathi, SM Roopan, CS Vasavi… - BioMed research …, 2014 - Wiley Online Library
An in vitro antidiabetic activity on α‐amylase and α–glucosidase activity of novel 10‐chloro‐
4‐(2‐chlorophenyl)‐12‐phenyl‐5, 6‐dihydropyrimido [4, 5‐a] acridin‐2‐amines (3a–3f) …

An update on oligosaccharides and their esters from traditional Chinese medicines: Chemical structures and biological activities

XY Chen, RF Wang, B Liu - Evidence‐Based Complementary …, 2015 - Wiley Online Library
A great number of naturally occurring oligosaccharides and oligosaccharide esters have
been isolated from traditional Chinese medicinal plants, which are used widely in Asia and …