A review on antimicrobial peptides databases and the computational tools
Abstract Antimicrobial Peptides (AMPs) have been considered as potential alternatives for
infection therapeutics since antibiotic resistance has been raised as a global problem. The …
infection therapeutics since antibiotic resistance has been raised as a global problem. The …
Measuring microtubule dynamics
Microtubules are key players in cellular self-organization, acting as structural scaffolds,
cellular highways, force generators and signalling platforms. Microtubules are polar …
cellular highways, force generators and signalling platforms. Microtubules are polar …
[HTML][HTML] Late endosomes act as mRNA translation platforms and sustain mitochondria in axons
Local translation regulates the axonal proteome, playing an important role in neuronal
wiring and axon maintenance. How axonal mRNAs are localized to specific subcellular sites …
wiring and axon maintenance. How axonal mRNAs are localized to specific subcellular sites …
Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution
Introduction In vivo imaging provides a window into the spatially complex, rapidly evolving
physiology of the cell that structural imaging alone cannot. However, observing this …
physiology of the cell that structural imaging alone cannot. However, observing this …
Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution
We present cleared-tissue axially swept light-sheet microscopy (ctASLM), which enables
isotropic, subcellular resolution imaging with high optical sectioning capability and a large …
isotropic, subcellular resolution imaging with high optical sectioning capability and a large …
[HTML][HTML] Photoswitchable inhibitors of microtubule dynamics optically control mitosis and cell death
M Borowiak, W Nahaboo, M Reynders, K Nekolla… - Cell, 2015 - cell.com
Small molecules that interfere with microtubule dynamics, such as Taxol and the Vinca
alkaloids, are widely used in cell biology research and as clinical anticancer drugs …
alkaloids, are widely used in cell biology research and as clinical anticancer drugs …
[HTML][HTML] Phase separation of TPX2 enhances and spatially coordinates microtubule nucleation
Phase separation of substrates and effectors is proposed to enhance biological reaction
rates and efficiency. Targeting protein for Xklp2 (TPX2) is an effector of branching …
rates and efficiency. Targeting protein for Xklp2 (TPX2) is an effector of branching …
[HTML][HTML] Vimentin intermediate filaments template microtubule networks to enhance persistence in cell polarity and directed migration
Z Gan, L Ding, CJ Burckhardt, J Lowery, A Zaritsky… - Cell systems, 2016 - cell.com
Increased expression of vimentin intermediate filaments (VIFs) enhances directed cell
migration, but the mechanism behind VIFs' effect on motility is not understood. VIFs interact …
migration, but the mechanism behind VIFs' effect on motility is not understood. VIFs interact …
XMAP215 is a microtubule nucleation factor that functions synergistically with the γ-tubulin ring complex
How microtubules (MTs) are generated in the cell is a major question in understanding how
the cytoskeleton is assembled. For several decades, γ-tubulin has been accepted as the …
the cytoskeleton is assembled. For several decades, γ-tubulin has been accepted as the …
Accelerated actin filament polymerization from microtubule plus ends
JL Henty-Ridilla, A Rankova, JA Eskin, K Kenny… - Science, 2016 - science.org
Microtubules (MTs) govern actin network remodeling in a wide range of biological
processes, yet the mechanisms underlying this cytoskeletal cross-talk have remained …
processes, yet the mechanisms underlying this cytoskeletal cross-talk have remained …