A review on antimicrobial peptides databases and the computational tools

S Ramazi, N Mohammadi, A Allahverdi, E Khalili… - Database, 2022 - academic.oup.com
Abstract Antimicrobial Peptides (AMPs) have been considered as potential alternatives for
infection therapeutics since antibiotic resistance has been raised as a global problem. The …

Measuring microtubule dynamics

AJ Zwetsloot, G Tut, A Straube - Essays in biochemistry, 2018 - portlandpress.com
Microtubules are key players in cellular self-organization, acting as structural scaffolds,
cellular highways, force generators and signalling platforms. Microtubules are polar …

[HTML][HTML] Late endosomes act as mRNA translation platforms and sustain mitochondria in axons

JM Cioni, JQ Lin, AV Holtermann, M Koppers… - Cell, 2019 - cell.com
Local translation regulates the axonal proteome, playing an important role in neuronal
wiring and axon maintenance. How axonal mRNAs are localized to specific subcellular sites …

Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution

BC Chen, WR Legant, K Wang, L Shao, DE Milkie… - Science, 2014 - science.org
Introduction In vivo imaging provides a window into the spatially complex, rapidly evolving
physiology of the cell that structural imaging alone cannot. However, observing this …

Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution

T Chakraborty, MK Driscoll, E Jeffery, MM Murphy… - Nature …, 2019 - nature.com
We present cleared-tissue axially swept light-sheet microscopy (ctASLM), which enables
isotropic, subcellular resolution imaging with high optical sectioning capability and a large …

[HTML][HTML] Photoswitchable inhibitors of microtubule dynamics optically control mitosis and cell death

M Borowiak, W Nahaboo, M Reynders, K Nekolla… - Cell, 2015 - cell.com
Small molecules that interfere with microtubule dynamics, such as Taxol and the Vinca
alkaloids, are widely used in cell biology research and as clinical anticancer drugs …

[HTML][HTML] Phase separation of TPX2 enhances and spatially coordinates microtubule nucleation

MR King, S Petry - Nature communications, 2020 - nature.com
Phase separation of substrates and effectors is proposed to enhance biological reaction
rates and efficiency. Targeting protein for Xklp2 (TPX2) is an effector of branching …

[HTML][HTML] Vimentin intermediate filaments template microtubule networks to enhance persistence in cell polarity and directed migration

Z Gan, L Ding, CJ Burckhardt, J Lowery, A Zaritsky… - Cell systems, 2016 - cell.com
Increased expression of vimentin intermediate filaments (VIFs) enhances directed cell
migration, but the mechanism behind VIFs' effect on motility is not understood. VIFs interact …

XMAP215 is a microtubule nucleation factor that functions synergistically with the γ-tubulin ring complex

A Thawani, RS Kadzik, S Petry - Nature cell biology, 2018 - nature.com
How microtubules (MTs) are generated in the cell is a major question in understanding how
the cytoskeleton is assembled. For several decades, γ-tubulin has been accepted as the …

Accelerated actin filament polymerization from microtubule plus ends

JL Henty-Ridilla, A Rankova, JA Eskin, K Kenny… - Science, 2016 - science.org
Microtubules (MTs) govern actin network remodeling in a wide range of biological
processes, yet the mechanisms underlying this cytoskeletal cross-talk have remained …