Lipids and lipid metabolism are critical factors in hair follicle (HF) biology, and cholesterol
has long been suspected of influencing hair growth. Altered cholesterol homeostasis is …

Effective cholesterol homoeostasis is essential in maintaining cellular function, and this is
achieved by a network of lipid-responsive nuclear transcription factors, and enzymes …

StarD4 is a member of the StarD4 subfamily of START domain proteins with a characteristic
lipid binding pocket specific for cholesterol. The objective of this study was to define StarD4 …

Complex mechanisms regulate the cellular distribution of cholesterol, a critical component of
eukaryote membranes involved in regulation of membrane protein functions directly and …

Steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domain proteins
display diverse expression patterns and cellular localisations. They bind a large variety of …

Steroidogenic acute regulatory-related lipid transfer (START) domain proteins are involved
in the nonvesicular intracellular transport of lipids and sterols. The STARD1 (STARD1 and …

Cedrela odorata L. is a native plant of the Amazon region. The bark is used in folk remedies
for the treatment of diarrhea, vomiting, fever and inflammation. Atopic dermatitis (AD) is a …

StarD5 belongs to the StarD4 subfamily of steroidogenic acute regulatory lipid transfer
(START) domain proteins. In macrophages, StarD5 is found in the cytosol and maintains a …

We present herein a review of our recent results on the characterization of the binding sites
of STARD1, STARD5 and STARD6 using NMR and other biophysical techniques. Whereas …

The importance of cholesterol in hair follicle biology is underscored by its links to the
pathogenesis of alopecias and hair growth disorders. Reports have associated defects in …