Cell death can be executed through different subroutines. Since the description of
ferroptosis as an iron-dependent form of non-apoptotic cell death in 2012, there has been …

It has been 15 years since the birth of human induced pluripotent stem cell (iPSC)
technology in 2007, and the scope of its application has been expanding. In addition to the …

Redox balance is essential for normal brain, hence dis-coordinated oxidative reactions
leading to neuronal death, including programs of regulated death, are commonly viewed as …

Growing evidence has indicated that iron deposition is one of the key factors leading to
neuronal death in the neurodegenerative diseases. Ferritin is a hollow iron storage protein …

Disruption of cerebral iron regulation appears to have a role in aging and in the
pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron …

Iron is indispensable for normal body functions across species because of its critical roles in
red blood cell function and many essential proteins and enzymes required for numerous …

Iron is an essential element for the development and functionality of the brain, and
anomalies in its distribution and concentration in brain tissue have been found to be …

Background Dementia is common in Parkinson's disease (PD) but measures that track
cognitive change in PD are lacking. Brain tissue iron accumulates with age and co-localises …

Significance: Alzheimer's disease (AD) is the most common cause of dementia in the elderly.
AD is currently ranked as the sixth leading cause of death, but some sources put it as third …

Despite significant developments and persistent efforts by scientists, cancer is one of the
primary causes of human death worldwide. No form of life on Earth can survive without iron …