Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading
cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive …

Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

Nitric oxide (NO) is a free radical acting as a cellular signaling molecule in many different
biochemical processes. NO is synthesized from l-arginine through the action of the nitric …

Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of
metabolic syndrome and has become the major cause of chronic liver disease, especially in …

Total absence of adipose tissue (lipoatrophy) is associated with the development of severe
metabolic disorders including hepatomegaly and fatty liver. Here, we sought to investigate …

Oxidative and nitrosative stress plays a pivotal role in the incidence of metabolic disorders.
Studies from this lab and others in iNOS-/-mice have demonstrated occurrence of insulin …

The role of oxidative and nitrosative stress has been implied in both physiology and
pathophysiology of metabolic disorders. Inducible nitric oxide synthase (iNOS) has emerged …

iNOS, an important mediator of inflammation, has emerged as an important metabolic
regulator. There are conflicting observations on the incidence of insulin resistance (IR) due …

Oxidative and nitrosative stress play pivotal roles in normal physiological processes and the
pathogenesis of metabolic disorders. Previous studies from our lab demonstrated insulin …

This study investigated whether chronic undernutrition alters the mitochondrial structure and
function in renal proximal tubule cells, thus impairing fluid transport and homeostasis. We …