Ever since microRNAs (miRNAs) were first recognized as an extensive gene family> 20
years ago, a broad community of researchers was drawn to investigate the universe of small …

MicroRNAs (miRNAs) are versatile, post-transcriptional regulators of gene expression.
Canonical miRNAs are generated through the two-step DROSHA-and DICER-mediated …

MicroRNAs (miRNAs) typically direct degradation of their mRNA targets. However, some
targets have unusual miRNA-binding sites that direct degradation of cognate miRNAs …

Low expression levels and stoichiometric imbalances of long noncoding RNAs (lncRNAs)
are often used as evidence for their probable lack of function or for limiting the scope of their …

MicroRNAs (miRNAs) post-transcriptionally repress gene expression by guiding Argonaute
(AGO) proteins to target mRNAs. While much is known about the regulation of miRNA …

MicroRNAs (miRNAs) pair to sites in mRNAs to direct the degradation of these RNA
transcripts. Conversely, certain RNA transcripts can direct the degradation of particular …

MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression that play critical
roles in development and disease. Target-directed miRNA degradation (TDMD), a pathway …

MicroRNAs are a class of small regulatory RNAs that mediate regulation of protein synthesis
by recognizing sequence elements in mRNAs. MicroRNAs are processed through a series …

MicroRNAs (miRNA) load onto AGO proteins to target mRNAs for translational repression or
degradation. However, miRNA degradation can be triggered when extensively base-paired …

Chronic non-healing wounds, a prevalent complication of diabetes, are associated with
increased mortality in diabetic patients. Excessive accumulation of M1 macrophages in …