Advances in oral controlled drug delivery: the role of drug–polymer and interpolymer non-covalent interactions

S De Robertis, MC Bonferoni, L Elviri… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: After more than four decades of intense research, oral controlled drug delivery
systems (DDSs) still represent a topic of major interest for pharmaceutical scientist and …

Alginate graft copolymers and alginate–co-excipient physical mixture in oral drug delivery

TW Wong - Journal of Pharmacy and Pharmacology, 2011 - academic.oup.com
Objectives Use of alginate graft copolymers in oral drug delivery reduces dosage form
manufacture complexity with reference to mixing or coating processes. It is deemed to give …

Synthesis and characterization of silica nanoparticles with well-defined thermoresponsive PNIPAM via a combination of RAFT and click chemistry

J Chen, M Liu, C Chen, H Gong… - ACS applied materials & …, 2011 - ACS Publications
Covalent functionalization of azide-modified SiO2 with well-defined, alkyne-terminated poly
(N-isopropylacrylamide) was accomplished by the Cu (I)-catalyzed [3+ 2] Huisgen …

Synthesis and Self-Assembly of Thermoresponsive PEG-b-PNIPAM-b-PCL ABC Triblock Copolymer through the Combination of Atom Transfer Radical …

J Chen, M Liu, H Gong, Y Huang… - The Journal of Physical …, 2011 - ACS Publications
A well-defined thermoresponsive poly (ethylene glycol)-block-poly (N-isopropylacrylamide)-
block-poly (ε-caprolactone)(PEG43-b-PNIPAM82-b-PCL87) triblock copolymer was …

Micellization and gelatinization in aqueous media of pH-and thermo-responsive amphiphilic ABC (PMMA 82-b-PDMAEMA 150-b-PNIPAM 65) triblock copolymer …

Y Huang, P Yong, Y Chen, Y Gao, W Xu, Y Lv, L Yang… - RSC Advances, 2017 - pubs.rsc.org
The multi-stimuli-responsive amphiphilic ABC triblock copolymer of poly (methyl
methacrylate)-block-poly [N, N-(dimethylamino) ethyl methacrylate]-block-poly (N …

Eudragit E PO as a complementary material for designing oral drug delivery systems with controlled release properties: comparative evaluation of new …

RI Moustafine, AV Bukhovets, AY Sitenkov… - Molecular …, 2013 - ACS Publications
The design of new interpolyelectrolyte complexes (IPEC) between countercharged polymers
(Eudragit EPO (EPO) and Eudragit L100 (L100)) was investigated. The formation and …

Hydrophilic drug encapsulation in shell-core microcarriers by two stage polyelectrolyte complexation method

A Dalmoro, AY Sitenkov, S Cascone, G Lamberti… - International Journal of …, 2017 - Elsevier
In this study a protocol exploiting the combination of the ultrasonic atomization and the
complexation between polyelectrolytes was developed to efficiently encapsulate a …

Interpolymer Complexes of Eudragit® Copolymers as Novel Carriers for Colon-Specific Drug Delivery

AV Bukhovets, N Fotaki, VV Khutoryanskiy… - Polymers, 2020 - mdpi.com
Interpolymer complexes (IPC) based on Eudragit® EPO and Eudragit® S100 were
investigated as potential carriers for oral controlled drug delivery to the colon. IPC samples …

Characteristics of Interpolyelectrolyte Complexes Based on Different Types of Pectin with Eudragit® EPO as Novel Carriers for Colon-Specific Drug Delivery

SF Nasibullin, JV Dunaeva, LA Akramova… - International Journal of …, 2023 - mdpi.com
Given that pectin is a well-known substance used for drug delivery, we aimed to obtain and
further examine the efficacy of interpolyelectrolyte complexes based on citrus or apple pectin …

Development of novel EE/alginate polyelectrolyte complex nanoparticles for lysozyme delivery: physicochemical properties and in vitro safety

S Sepúlveda-Rivas, HF Fritz, C Valenzuela… - Pharmaceutics, 2019 - mdpi.com
The number of biologic drugs has increased in the pharmaceutical industry due to their high
therapeutic efficacy and selectivity. As such, safe and biocompatible delivery systems to …