Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis

YJ Lin, M Anzaghe, S Schülke - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally.
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …

Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction

VM Holers, MK Demoruelle, KA Kuhn… - Nature Reviews …, 2018 - nature.com
Individuals at high risk of developing seropositive rheumatoid arthritis (RA) can be identified
for translational research and disease prevention studies through the presence of highly …

Understanding the role of cytokines in the pathogenesis of rheumatoid arthritis

S Mateen, A Zafar, S Moin, AQ Khan, S Zubair - Clinica chimica acta, 2016 - Elsevier
Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disease of unknown
etiology. It is characterized by the presence of rheumatoid factor and anti-citrullinated …

Impacts of microbiome metabolites on immune regulation and autoimmunity

S Haase, A Haghikia, N Wilck, DN Müller… - …, 2018 - Wiley Online Library
A vast number of studies have demonstrated a remarkable role for the gut microbiota and
their metabolites in the pathogenesis of inflammatory diseases, including multiple sclerosis …

A role for Th1-like Th17 cells in the pathogenesis of inflammatory and autoimmune disorders

AN Kamali, SM Noorbakhsh, H Hamedifar… - Molecular …, 2019 - Elsevier
Abstract The T helper 17 (Th17) cells contain a dynamic subset of CD4+ T-cells that are able
to develop into other different lineage subsets, including the Th1-like Th17 cells. These cells …

Interleukin-17 in human inflammatory diseases

AG Shabgah, E Fattahi, FZ Shahneh - Advances in Dermatology and …, 2014 - termedia.pl
Human Th17 pro-inflammatory cells are currently defined as cells that produce IL-17A and F,
tumor necrosis factor (TNF)-α, IL-6, IL-21, IL-22 and IL-23. Recently discovered related …

Dendritic cells, T cells and their interaction in rheumatoid arthritis

P Wehr, H Purvis, SC Law… - Clinical & Experimental …, 2019 - academic.oup.com
Dendritic cells (DCs) are the key professional antigen-presenting cells which bridge innate
and adaptive immune responses, inducing the priming and differentiation of naive to effector …

Immune regulatory network in successful pregnancy and reproductive failures

M Ghaebi, M Nouri, A Ghasemzadeh, L Farzadi… - Biomedicine & …, 2017 - Elsevier
Maternal immune system must tolerate semiallogenic fetus to establish and maintain a
successful pregnancy. Despite the existence of several strategies of trophoblast to avoid …

Periodontitis and rheumatoid arthritis: an update 2012‐2017

PM Bartold, I Lopez‐Oliva - Periodontology 2000, 2020 - Wiley Online Library
Rheumatoid arthritis and chronic periodontitis are both chronic inflammatory diseases
characterized by an exacerbated inflammatory reaction that leads to destruction of bone and …

[HTML][HTML] Amelioration of clinical symptoms of patients with refractory rheumatoid arthritis following treatment with autologous bone marrow-derived mesenchymal stem …

M Ghoryani, Z Shariati-Sarabi… - Biomedicine & …, 2019 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune arthropathy characterized
by synovial hyperplasia leading to functional impairment. Although the exact cause of RA is …