Cell–Material Interplay in Focal Adhesion Points

K Berniak, DP Ura, A Piórkowski… - ACS Applied Materials …, 2024 - ACS Publications
The complex interplay between cells and materials is a key focus of this research, aiming to
develop optimal scaffolds for regenerative medicine. The need for tissue regeneration …

Harnessing Fungi Signaling in Living Composites

S Schyck, P Marchese, M Amani, M Ablonczy… - Global …, 2024 - Wiley Online Library
Signaling pathways in fungi offer a profound avenue for harnessing cellular communication
and have garnered considerable interest in biomaterial engineering. Fungi respond to …

Label-free pathogen detection based on yttrium-doped carbon nanoparticles up to single-cell resolution

M Alafeef, K Dighe, D Pan - ACS applied materials & interfaces, 2019 - ACS Publications
The capability to detect bacteria at a low cell density is critical to prevent the delay in
therapeutic intervention and to avoid the emergence of antibiotic-resistant species. Till date …

Three‐dimensional imaging and quantification of real‐time cytosolic calcium oscillations in microglial cells cultured on electrospun matrices using laser scanning …

K Venkateswarlu, G Suman, V Dhyani… - Biotechnology and …, 2020 - Wiley Online Library
The development of a minimally invasive, robust, and inexpensive technique that permits
real‐time monitoring of cell responses on biomaterial scaffolds can improve the eventual …

The mitochondrial calcium uniporter inhibitor Ru265 increases neuronal excitability and reduces neurotransmission via off‐target effects

P Xu, S Swain, RJ Novorolsky, E Garcia… - British Journal of …, 2024 - Wiley Online Library
Abstract Background and Purpose Excitotoxicity due to mitochondrial calcium (Ca2+)
overloading can trigger neuronal cell death in a variety of pathologies. Inhibiting the …

Mapping of structural arrangement of cells and collective calcium transients: an integrated framework combining live cell imaging using confocal microscopy and …

S Gare, S Chel, TK Abhinav, V Dhyani… - Integrative …, 2022 - academic.oup.com
Abstract Live cell calcium (Ca2+) imaging is one of the important tools to record cellular
activity during in vitro and in vivo preclinical studies. Specially, high-resolution microscopy …

A robust model system for retinal hypoxia: live imaging of calcium dynamics and gene expression studies in primary human mixed retinal culture

S Shahulhameed, S Swain, S Jana… - Frontiers in …, 2020 - frontiersin.org
The detailed mechanisms underlying oxidative stress that leads to neuroinflammation and
neurodegeneration in retinal vascular conditions, including diabetic retinopathy, retinopathy …

A computational model to uncover the biophysical underpinnings of neural firing heterogeneity in dissociated hippocampal cultures

V Dhyani, K George, S Gare, KV Venkatesh… - …, 2023 - Wiley Online Library
Abstract Calcium (Ca2+) imaging reveals a variety of correlated firing in cultures of
dissociated hippocampal neurons, pinpointing the non‐synaptic paracrine release of …

Detection of Specific Templates in Calcium Spiking in HeLa Cells Using Hierarchical DBSCAN: Clustering and Visualization of CellDrug Interaction at Multiple Doses

S Chel, S Gare, L Giri - … Conference of the IEEE Engineering in …, 2020 - ieeexplore.ieee.org
One of the major challenges in analyzing large scale intracellular calcium spiking data
obtained through fluorescent imaging is to identify various patterns present in time series …

Quantitative confocal microscopy for grouping of dose–response data: deciphering calcium sequestration and subsequent cell death in the presence of excess …

K Manohar, S Gare, S Chel… - SLAS TECHNOLOGY …, 2021 - journals.sagepub.com
Fluorescent calcium (Ca2+) imaging is one of the preferred methods to record cellular
activity during in vitro preclinical studies, high-content drug screening, and toxicity analysis …