Patient centric pharmaceutical drug product design—The impact on medication adherence

E Menditto, V Orlando, G De Rosa, P Minghetti… - Pharmaceutics, 2020 - mdpi.com
Medication adherence is a growing concern for public health and poor adherence to therapy
has been associated with poor health outcomes and higher costs for patients. Interventions …

[HTML][HTML] Methodologies for assessing the acceptability of oral formulations among children and older adults: a systematic review

SR Ranmal, F O'Brien, F Lopez, F Ruiz, M Orlu… - Drug discovery today, 2018 - Elsevier
Highlights•Patient acceptability is crucial for pharmaceutical products.•We review
acceptability assessment methods in paediatric and geriatric patients.•The published …

Personalized orodispersible films by hot melt ram extrusion 3D printing

UM Musazzi, F Selmin, MA Ortenzi… - International journal of …, 2018 - Elsevier
This work demonstrates the feasibility of the extemporaneous preparation of maltodextrins
orodispersible films (ODF) by hot-melt ram-extrusion 3D printing. This method consists of …

Semi-solid extrusion 3D printing ODFs: an individual drug delivery system for small scale pharmacy

TT Yan, ZF Lv, P Tian, MM Lin, W Lin… - Drug development …, 2020 - Taylor & Francis
Orodispersible films (ODFs) are promising drug delivery systems for customized medicines
as it provide an alternative approach to increase consumer acceptance by advantages of …

Tablet scoring: current practice, fundamentals, and knowledge gaps

ER Jacques, P Alexandridis - Applied Sciences, 2019 - mdpi.com
Oral solid dosage formulations and/or tablets have remained the preferred route of
administration by both patients and health care practitioners. Oral tablets are easy to …

Customized oral mucosal adhesive film-based functional-substance delivery system using embedded 3D printing method

JY Yu, HW Kim, HJ Park - Food Hydrocolloids, 2022 - Elsevier
Oral mucosal adhesive films (OMAFs) have attracted attention as delivery systems for the
easy ingestion of functional substances. However, conventional casting-based production …

[HTML][HTML] Comparison of tablet splitting techniques for dosing accuracy of nebivolol tablets: Hand splitting versus tablet cutter and knife

S Olgac, DY Usta, T Incecayir - Saudi Pharmaceutical Journal, 2021 - Elsevier
Tablet splitting is a common practice in clinical settings to lower doses, facilitate swallowing
or save costs. Splitting devices can be used when hand splitting is difficult or painful …

Concerns regarding tablet splitting: a systematic review

AK Saran, NA Holden, SR Garrison - BJGP open, 2022 - bjgpopen.org
Background Tablet splitting can provide dose flexibility and cost savings; however,
pharmaceutical representatives typically discourage the practice. Aim To identify and …

Effect of different splitting techniques on the characteristics of divided tablets of five commonly split drug products in Jordan

SF Gharaibeh, L Tahaineh - Pharmacy Practice (Granada), 2020 - SciELO Espana
Resumen GHARAIBEH, Shadi F y TAHAINEH, Linda. Effect of different splitting techniques
on the characteristics of divided tablets of five commonly split drug products in Jordan …

The development of a test battery to assess the hand–eye functions relevant in predicting easy and accurate tablet subdivision in older people: A pilot study

D van Riet–Nales, L Donkerbroek… - British Journal of …, 2020 - Wiley Online Library
Aims Tablets may be subdivided for dose adaptations or to ease swallowing. The handling
is common in older patients but can be difficult and inaccurate. Currently, it is not known …