The prognostication of colorectal cancer (CRC) has traditionally relied on staging as defined
by the Union for International Cancer Control (UICC) and American Joint Committee on …

Colorectal cancer is the fourth most common noncutaneous malignancy in the United States
and the second most frequent cause of cancer-related death. Over the past 12 years …

Caspase‐3 (CASP3) is a major mediator of apoptosis activated during cellular exposure to
cytotoxic drugs, radiotherapy or immunotherapy. It is often used as a marker for efficacy of …

Purpose The sixth edition of American Joint Committee on Cancer (AJCC) Cancer Staging
Manual for colon cancer subdivided stage II into IIA (T3N0) and IIB (T4N0) and stage III into …

BACKGROUND: The presence or absence of lymph node metastases is known to be an
important prognostic factor for patients with pancreatic cancer. Few studies have …

Objective: To determine whether analyzing more lymph nodes in colon cancer specimens
improves survival. Summary Background Data: Increasing the number of lymph nodes …

Objective: To investigate whether the number of lymph nodes metastasis (LNMs) and the
ratio between metastatic and examined lymph nodes (LNs) are better prognostic factors …

Background Based on data from other malignancies, the number of lymph nodes evaluated
and the ratio of metastatic to examined lymph nodes (LNR) may be important predictors of …

Purpose The purpose of this study was to examine the impact of the number of negative
lymph nodes on survival in patients with stage III colon cancer. Patients and Methods …

Purpose: To investigate whether the ratio between metastatic and examined lymph nodes (N
ratio) is a better prognostic factor as compared with traditional staging systems in patients …