The objective was to provide the current state of the art regarding the role of vitamin D in
chronic diseases (osteoporosis, cancer, cardiovascular diseases, dementia, autism, type 1 …

Vitamin D is a versatile signalling molecule with a well-established role in the regulation of
calcium homeostasis and bone health. The spectrum of vitamin D target organs has …

Abstract The cytochrome P450 (P450) enzymes first attracted interest because of their
relevance to the metabolism of drugs, steroids, and carcinogens. Collectively, the 57 human …

In the last decade, vitamin D has emerged as a pleiotropic molecule with a multitude of
autocrine, paracrine and endocrine functions, mediated by classical genomic as well as non …

The steroid hormone vitamin D is historically recognized for its relevance to bone health and
calcium homeostasis. Recent years have witnessed a shift in focus to non-skeletal benefits …

Context Results of animal models and cross-sectional cohort studies have suggested a
beneficial role for vitamin D in male reproduction. Objective Determine the effect of vitamin D …

STUDY QUESTION Are low vitamin D levels linked with semen quality and sex steroids in
infertile men? SUMMARY ANSWER Infertile men with vitamin D deficiency had lower sperm …

Spermatogenesis, an elaborate and male-specific process in adult testes by which a number
of spermatozoa are produced constantly for male fertility, relies on spermatogonial stem …

Asthenozoospermia (AZS), defined by reduced motility or absent sperm motility, is one of the
main causes of male infertility. This condition may be divided into isolated AZS in the …

To date, the key role of vitamin D in male reproductive system has been suggested, since
the expression of vitamin D receptors and metabolizing enzymes was demonstrated in the …