Photocatalytic late-stage C–H functionalization

P Bellotti, HM Huang, T Faber, F Glorius - Chemical Reviews, 2023 - ACS Publications
The emergence of modern photocatalysis, characterized by mildness and selectivity, has
significantly spurred innovative late-stage C–H functionalization approaches that make use …

Radical C(sp3)–H functionalization and cross-coupling reactions

DL Golden, SE Suh, SS Stahl - Nature Reviews Chemistry, 2022 - nature.com
C–H functionalization reactions are playing an increasing role in the preparation and
modification of complex organic molecules, including pharmaceuticals, agrochemicals and …

Photoredox-catalyzed C–H functionalization reactions

N Holmberg-Douglas, DA Nicewicz - Chemical reviews, 2021 - ACS Publications
The fields of C–H functionalization and photoredox catalysis have garnered enormous
interest and utility in the past several decades. Many different scientific disciplines have …

Metallaphotoredox catalysis for sp 3 C–H functionalizations through hydrogen atom transfer (HAT)

J Zhang, M Rueping - Chemical Society Reviews, 2023 - pubs.rsc.org
In recent years, the integration of photocatalytic hydrogen atom transfer (HAT) with transition
metal catalysis has emerged as a formidable strategy for the construction of C (sp3)–carbon …

Photoinduced Site-Selective Functionalization of Aliphatic C–H Bonds by Pyridine N-oxide Based HAT Catalysts

B Wang, C Ascenzi Pettenuzzo, J Singh… - ACS …, 2022 - ACS Publications
Readily available and facilely tunable pyridine N-oxides have been developed as effective
photoinduced hydrogen-atom-transfer (HAT) catalysts for site-selective C–H …

Cationic DABCO-based catalyst for site-selective C–H alkylation via photoinduced hydrogen-atom transfer

A Matsumoto, M Yamamoto, K Maruoka - ACS Catalysis, 2022 - ACS Publications
A series of hydrogen-atom transfer (HAT) catalysts based on the readily available and
tunable 1, 4-diazabicyclo [2.2. 2] octane (DABCO) structure was designed, and their …

Photocatalytic decarboxylative pyridylation of carboxylic acids using in situ-generated amidyl radicals as oxidants

C Kim, J Jeong, M Vellakkaran, S Hong - ACS Catalysis, 2022 - ACS Publications
Site-selective C–H functionalization of heteroarenes is important for the rapid modification of
bioactive molecules. Herein, we report an efficient photocatalytic platform for the visible-light …

Visible‐Light‐Induced C4‐Selective Functionalization of Pyridinium Salts with Cyclopropanols

M Vellakkaran, T Kim, S Hong - Angewandte Chemie, 2022 - Wiley Online Library
The site‐selective C− H functionalization of heteroarenes is of considerable importance for
streamlining the rapid modification of bioactive molecules. Herein, we report a general …

Identification of a self-photosensitizing hydrogen atom transfer organocatalyst system

H Fuse, Y Irie, M Fuki, Y Kobori, K Kato… - Journal of the …, 2022 - ACS Publications
We developed organocatalyst systems to promote the cleavage of stable C–H bonds, such
as formyl, α-hydroxy, and benzylic C–H bonds, through a hydrogen atom transfer (HAT) …

Directed photochemically mediated nickel-catalyzed (hetero) arylation of aliphatic C–H bonds

RT Simons, M Nandakumar, K Kwon… - Journal of the …, 2023 - ACS Publications
Site-selective functionalization of unactivated C (sp3)–H centers is challenging because of
the ubiquity and strength of alkyl C–H bonds. Herein, we disclose a position-selective C …