Among gut microbiota-derived metabolites, trimethylamine-N-oxide (TMAO) is receiving
increased attention due to its possible role in the carcinogenesis of colorectal cancer (CRC) …

Trimethylamine N-oxide (TMAO) is a biologically active molecule and is a putative promoter
of chronic diseases including atherosclerosis in humans. Host intestinal bacteria produce its …

Lipids are vital biological molecules and play multiple roles in cellular function of
mammalian organisms such as cellular membrane anchoring, signal transduction, material …

Background: Healthy dietary patterns that conform to national dietary guidelines are related
to lower chronic disease incidence and longer life span. However, the precise mechanisms …

Metabolomic epidemiology is the high-throughput study of the relationship between
metabolites and health-related traits. This emerging and rapidly growing field has improved …

Early detection of prostate cancer (PC) is largely carried out using assessment of prostate-
specific antigen (PSA) level; yet it cannot reliably discriminate between benign pathologies …

Trimethylamine-N-oxide (TMAO), a gut-derived metabolite, has recently emerged as a
candidate risk factor for cardiovascular disease and other adverse health outcomes …

Abstract Background: Trimethylamine-N-oxide (TMAO) is a metabolite of carnitine, choline,
and phosphatidylcholine, which is inversely associated with survival of cardiovascular …

ABSTRACT Background Trimethylamine-N-oxide (TMAO) is a gut microbiota–derived
metabolite produced from dietary nutrients. Many studies have discovered that circulating …

Anabolic metabolism mediated by aberrant growth factor signalling fuels tumour growth and
progression. The first biochemical descriptions of the altered metabolic nature of solid …