The liver microcirculatory milieu, mainly composed of liver sinusoidal endothelial cells
(LSECs), hepatic stellate cells (HSCs) and hepatic macrophages, has an essential role in …

Activin A receptor type I (ACVR1) encodes for a bone morphogenetic protein type I receptor
of the TGFβ receptor superfamily. It is involved in a wide variety of biological processes …

Here we provide a detailed protocol describing the clinical procedure of hepatic venous
pressure gradient (HVPG) measurement in patients with advanced chronic liver disease …

Meat and meat products have a high nutritional value. Besides major components, meat is
rich in bioactive components, primarily taurine, l-carnitine, choline, alpha-lipoic acid …

Compensated liver cirrhosis (CLC) is defined as cirrhosis with one or more decompensating
events, such as ascites, variceal haemorrhage, or hepatic encephalopathy. Patients with …

Background Cardiovascular disease (CVD) remains the foremost cause of mortality globally.
Taurine, an amino acid, holds promise for cardiovascular health through mechanisms such …

Background and Aims Portal hypertension (PH) is a major driver for cirrhosis complications.
Portal pressure is estimated in practice by the HVPG. The assessment of HVPG changes …

Cirrhosis is a leading cause of morbidity and mortality, impacting more than 120 million
people worldwide. Although geographic differences exist, etiologic factors such as alcohol …

Taurine (TAU) is a sulfur-containing amino acid abundantly found in the human body.
Endogenously, TAU is synthesized from cysteine in the liver. However, newborns rely …

Cirrhosis-induced heart injury and cardiomyopathy is a serious consequence of this
disease. It has been shown that bile duct ligated (BDL) animals could serve as an …