Acetylcholine (ACh) has a crucial role in the peripheral and central nervous systems. The
enzyme choline acetyltransferase (ChAT) is responsible for synthesizing ACh from acetyl …

Synchronous rhythms represent a core mechanism for sculpting temporal coordination of
neural activity in the brain-wide network. This review focuses on oscillations in the cerebral …

The theta rhythm is one of the largest and most sinusoidal activity patterns in the brain. Here
I survey progress in the field of theta rhythms research. I present arguments supporting the …

Theta oscillations represent the" on-line" state of the hippocampus. The extracellular
currents underlying theta waves are generated mainly by the entorhinal input, CA3 …

The hippocampus is one of a group of remarkable structures embedded within the brain's
medial temporal lobe. Long known to be important for memory, it has been a prime focus of …

As indicated by the profound cognitive impairments caused by cholinergic receptor
antagonists, cholinergic neurotransmission has a vital role in cognitive function, specifically …

At least five muscarinic receptors genes have been cloned and expressed. Muscarinic
receptors act via activation of G proteins: m1, m3 and m5 muscarinic receptors couple to …

Long-term potentiation (LTP) of synaptic transmission represents the cellular basis of
learning and memory. Astrocytes have been shown to regulate synaptic transmission and …

3.3. Electrophysiological basis of tonic firing in thalamic relay neurons 3.4. High frequency
(30-50 Hz) rhythms in thalamic neurons 3.5. Functional consequences of …

Based on recent molecular genetics, as well as functional and quantitative anatomical
studies, the basal forebrain (BF) cholinergic projections, once viewed as a diffuse system …