Reactive astrocytes in central nervous system injury: subgroup and potential therapy

GL Yu, Y Zhang, B Ning - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Traumatic central nervous system (CNS) injury, which includes both traumatic brain injury
(TBI) and spinal cord injury (SCI), is associated with irreversible loss of neurological function …

The putative role of neuroinflammation in the interaction between traumatic brain injuries, sleep, pain and other neuropsychiatric outcomes: a state-of-the-art review

A Herrero Babiloni, AA Baril… - Journal of clinical …, 2023 - mdpi.com
Sleep disturbances are widely prevalent following a traumatic brain injury (TBI) and have the
potential to contribute to numerous post-traumatic physiological, psychological, and …

Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway

J Wang, C Jiang, K Zhang, X Lan, X Chen… - Free radical biology and …, 2019 - Elsevier
Traumatic brain injury (TBI) is a principal cause of death and disability worldwide. Melatonin,
a hormone made by the pineal gland, is known to have anti-inflammatory and antioxidant …

Non-excitatory amino acids, melatonin, and free radicals: examining the role in stroke and aging

VJ Carretero, E Ramos, P Segura-Chama… - Antioxidants, 2023 - mdpi.com
The aim of this review is to explore the relationship between melatonin, free radicals, and
non-excitatory amino acids, and their role in stroke and aging. Melatonin has garnered …

The multiple protective roles and molecular mechanisms of melatonin and its precursor N-acetylserotonin in targeting brain injury and liver damage and in maintaining …

C Luo, Q Yang, Y Liu, S Zhou, J Jiang, RJ Reiter… - Free Radical Biology …, 2019 - Elsevier
Melatonin is a neurohormone associated with sleep and wakefulness and is mainly
produced by the pineal gland. Numerous physiological functions of melatonin have been …

Melatonin and/or erythropoietin combined with hypothermia in a piglet model of perinatal asphyxia

R Pang, A Avdic-Belltheus, C Meehan… - Brain …, 2021 - academic.oup.com
As therapeutic hypothermia is only partially protective for neonatal encephalopathy, safe
and effective adjunct therapies are urgently needed. Melatonin and erythropoietin show …

Melatonin in endometriosis: mechanistic understanding and clinical insight

Y Li, SW Hung, R Zhang, GCW Man, T Zhang… - Nutrients, 2022 - mdpi.com
Endometriosis is defined as the development of endometrial glands and stroma outside the
uterine cavity. Pathophysiology of this disease includes abnormal hormone profiles, cell …

Neuroprotective effect of melatonin against lipopolysaccharide-induced depressive-like behavior in mice

EH Taniguti, YS Ferreira, IJV Stupp… - Physiology & …, 2018 - Elsevier
Accumulating evidence indicates an interaction between inflammation and depression since
increased levels of pro-inflammatory cytokines are associated with depression-related …

Melatonin as a therapy for traumatic brain injury: a review of published evidence

N Osier, E McGreevy, L Pham, A Puccio, D Ren… - International journal of …, 2018 - mdpi.com
Melatonin (MEL) is a hormone that is produced in the brain and is known to bind to MEL-
specific receptors on neuronal membranes in several brain regions. MEL's documented …

Cortical electrical stimulation ameliorates traumatic brain injury-induced sensorimotor and cognitive deficits in rats

CW Kuo, MY Chang, HH Liu, XK He… - Frontiers in Neural …, 2021 - frontiersin.org
Objective: Individuals with different severities of traumatic brain injury (TBI) often suffer long-
lasting motor, sensory, neurological, or cognitive disturbances. To date, no neuromodulation …